| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGout | BBAminus | in-out | out-none | No_ligand | No_ligand | 39 - 376 | 26 |
| B | Inactive | DFGout | BBAminus | out-out | out-none | No_ligand | No_ligand | 40 - 375 | 24 |
Representative sequence - Chain B
44 54 64 74
gstdsLPGKF EDMYKLTSEL LGEGAYAKVQ GAVSLQNGKE
84 94 104 114
YAVKIIEKQA GHSRSRVFRE VETLYQCQGN KNILELIEFF
124 134 144 154
EDDTRFYLVF EKLQGGSILA HIQKQKHFNE REASRVVRDV
164 215 225 235
AAALDFLHTK GIAHRDLKPE NILCESPEKV SPVKICDFDL
245 255 265 275
GSgmklnnsc tpittpeltt pcgsaeYMAP EVVEVFTDQA
285 295 305 315
TFYDKRCDLW SLGVVLYIML SGYPPFvghc gadcgwdrge
325 335 345 355
vcrvcqnklf esiqegkyef pdkdWAHISS EAKDLISKLL
365 375
VRDAKQRLSA AQVLQHPWVQ gqapekg