MKNK1 (MAP kinase-interacting serine/threonine-protein kinase 1)

Group: CAMK

Uniprot: MKNK1_HUMAN

Domain boundary: 48 - 374

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q9BUB5-K1A
DFGout	BBAminus	2	2HW6A
DFGout	None	2	5WVDA

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-Q9BUB5-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	40 - 382	None	None	0
2HW6A	2.5	Inactive	DFGout	BBAminus	in-out	out-none	No_ligand	No_ligand	39 - 376	None	None	26
2HW6B	2.5	Inactive	DFGout	BBAminus	out-out	out-none	No_ligand	No_ligand	40 - 375	None	None	24
5WVDA	3.0	Inactive	DFGout	None	in-out	out-none	7UX	Type1	41 - 375	None	None	23
5WVDB	3.0	Inactive	DFGout	None	in-out	out-none	7UX	Type1	41 - 374	None	None	21

MKNK1 (MAP kinase-interacting serine/threonine-protein kinase 1)

Group: CAMK

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q9BUB5-K1A
DFGout	BBAminus	2	2HW6A
DFGout	None	2	5WVDA

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	MKNK1_HUMAN	AF-Q9BUB5-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	40 - 382	None	None	0
Homo sapiens	MKNK1_HUMAN	2HW6A	2.5	Inactive	DFGout	BBAminus	in-out	out-none	No_ligand	No_ligand	39 - 376	None	None	26
Homo sapiens	MKNK1_HUMAN	2HW6B	2.5	Inactive	DFGout	BBAminus	out-out	out-none	No_ligand	No_ligand	40 - 375	None	None	24
Homo sapiens	MKNK1_HUMAN	5WVDA	3.0	Inactive	DFGout	None	in-out	out-none	7UX	Type1	41 - 375	None	None	23
Homo sapiens	MKNK1_HUMAN	5WVDB	3.0	Inactive	DFGout	None	in-out	out-none	7UX	Type1	41 - 374	None	None	21

MKNK1 (MAP kinase-interacting serine/threonine-protein kinase 1)

No non-human structures known.