2GNI

PRKACA (cAMP-dependent protein kinase catalytic subunit alpha)
Group: AGC
Uniprot: KAPCA_BOVIN
Organism: Bos taurus
Domain boundary: 44 - 298
Resolu: 2.27

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in M77 Type1 11 - 351 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        11         21         31         41 
gnaaaakkgS EQESVKEFLA KAKEDFLKKW ENPAQNTAHL 
        51         61         71         81 
DQFERIKTIG TGSFGRVMLV KHMETGNHYA MKILDKQKVV 
        91        101        111        121 
KLKQIEHTLN EKRILQAVNF PFLVKLEFSF KDNSNLYMVM 
       131        141        151        161 
EYMPGGDMFS HLRRIGRFSE PHARFYAAQI VLTFEYLHSL 
       171        181        191        201 
DLIYRDLKPE NLLIDQQGYI KVADFGFAKR VKGRTWTLCG 
       211        221        231        241 
TPEYLAPEII LSKGYNKAVD WWALGVLIYE MAAGYPPFFA 
       251        261        271        281 
DQPIQIYEKI VSGKVRFPSH FSSDLKDLLR NLLQVDLTKR 
       291        301        311        321 
FGNLKNGVND IKNHKWFATT DWIAIYQRKV EAPFIPKFKG 
       331        341        351 
PGDTSNFDDY EEEEIRVSIN EKCGKEFSEF
Lower-case residues are disordered in structure.
Mutations: L50I,V124M,E128D,Q182K,T184A
Phosphorylation: X11,X198,X339