2FO0

ABL1 (Tyrosine-protein kinase ABL1)
Group: TYR
Uniprot: ABL1_HUMAN
Organism: Homo sapiens
Domain boundary: 242 - 495
Resolu: 2.27

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-in out-in P16 Type1.5_Back 46 - 511 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -         43         53         63 
mgqqpgkvlg dqrrepqgls eaARWNSKEN LLAGPSENDP 
        73         83         93        103 
NLFVALYDFV ASGDNTLSIT KGEKLRVLGY NHNGEWCEAQ 
       113        123        133        143 
TKNGQGWVPS NYITPVNSLE KHSWYHGPVS RNAAEYLLSS 
       153        163        173        183 
GINGSFLVRE SESSPGQRSI SLRYEGRVYH YRINTASDGK 
       193        203        213        223 
LYVSSESRFN TLAELVHHHS TVADGLITTL HYPAPKRNKP 
       233        243        253        263 
TVYGVSPNYD KWEMERTDIT MKHKLGGGQY GEVYEGVWKK 
       273        283        293        303 
YSLTVAVKTL KEDTMEVEEF LKEAAVMKEI KHPNLVQLLG 
       313        323        333        343 
VCTREPPFYI ITEFMTYGNL LDYLRECNRQ EVNAVVLLYM 
       353        363        373        383 
ATQISSAMEY LEKKNFIHRN LAARNCLVGE NHLVKVADFG 
       393        403        413        423 
LSRLMTGDTY TAHAGAKFPI KWTAPESLAY NKFSIKSDVW 
       433        443        453        463 
AFGVLLWEIA TYGMSPYPGI DLSQVYELLE KDYRMERPEG 
       473        483        493        503 
CPEKVYELMR ACWQWNPSDR PSFAEIHQAF ETMFQESSIS 
         - 
DEVEKELGke nlygq
Lower-case residues are disordered in structure.
Mutations: D363N
Phosphorylation: X50