1SM2

ITK (Tyrosine-protein kinase ITK/TSK)
Group: TYR
Uniprot: ITK_HUMAN
Organism: Homo sapiens
Domain boundary: 363 - 614
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out none-none STU Type1 357 - 619 18
B Inactive DFGin None out-out none-none STU Type1 358 - 617 19
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       366        376        386        396 
vIDPSELTFV QEIGSGQFGL VHLGYWLNKD KVAIKTIREG 
       406        416        426        436 
AMSEEDFIEE AEVMMKLSHP KLVQLYGVCL EQAPICLVFE 
       446        456        466        476 
FMEHGCLSDY LRTQRGLFAA ETLLGMCLDV CEGMAYLEEA 
       486        496        506        516 
CVIHRDLAAR NCLVGENQVI KVSDFgmtrf vlddqytsst 
       526        536        546        556 
gtkfPVKWAS PEVFSFSRYS SKSDVWSFGV LMWEVFSEGK 
       566        576        586        596 
IPYENRSNSE VVEDISTGFR LYKPRLASTH VYQIMNHCWK 
       606        616 
ERPEDRPAFS RLLRQLAEIA Esgl
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None