1IR3

INSR (Insulin receptor)
Group: TYR
Uniprot: INSR_HUMAN
Organism: Homo sapiens
Domain boundary: 1023 - 1292
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in ANP Type1 1008 - 1310 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1014       1024       1034       1044 
vfpSSVFVPD EWEVSREKIT LLRELGQGSF GMVYEGNARD 
      1054       1064       1074       1084 
IIKGEAETRV AVKTVNESAS LRERIEFLNE ASVMKGFTCH 
      1094       1104       1114       1124 
HVVRLLGVVS KGQPTLVVME LMAHGDLKSY LRSLRPEAEN 
      1134       1144       1154       1164 
NPGRPPPTLQ EMIQMAAEIA DGMAYLNAKK FVHRDLAARN 
      1174       1184       1194       1204 
CMVAHDFTVK IGDFGMTRDI YETDYYRKGG KGLLPVRWMA 
      1214       1224       1234       1244 
PESLKDGVFT TSSDMWSFGV VLWEITSLAE QPYQGLSNEQ 
      1254       1264       1274       1284 
VLKFVMDGGY LDQPDNCPER VTDLMRMCWQ FNPKMRPTFL 
      1294       1304 
EIVNLLKDDL HPSFPEVSFF HSEENK
Lower-case residues are disordered in structure.
Mutations: C1008S,Y1011F
Phosphorylation: X1185,X1189,X1190