1CM8

MAPK12 (Mitogen-activated protein kinase 12)
Group: CMGC
Uniprot: MK12_HUMAN
Organism: Homo sapiens
Domain boundary: 27 - 311
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ANP Type1 8 - 353 0
B Active DFGin BLAminus in-in in-in ANP Type1 8 - 353 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        10         20         30         40 
msspppaRSG FYRQEVTKTA WEVRAVYRDL QPVgsgaygA 
        50         60         70         80 
VCSAVDGRTG AKVAIKKLYR PFQSELFAKR AYRELRLLKH 
        90        100        110        120 
MRHENVIGLL DVFTPDETLD DFTDFYLVMP FMGTDLGKLM 
       130        140        150        160 
KHEKLGEDRI QFLVYQMLKG LRYIHAAGII HRDLKPGNLA 
       170        180        190        200 
VNEDCELKIL DFGLARQADS EMTGYVVTRW YRAPEVILNW 
       210        220        230        240 
MRYTQTVDIW SVGCIMAEMI TGKTLFKGSD HLDQLKEIMK 
       250        260        270        280 
VTGTPPAEFV QRLQSDEAKN YMKGLPELEK KDFASILTNA 
       290        300        310        320 
SPLAVNLLEK MLVLDAEQRV TAGEALAHPY FESLHdtede 
       330        340        350        360 
pQVQKYDDSf ddvdRTLDEW KRVTYKEVLS FKPprqlgar 

vsketpl
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X183,X185