Ligand

Protein kinases in complex with NJV (Selonsertib)

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	4	6OYTD

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTA	2.824	None	DFGin	BLAminus	in-in	in-none	NJV	Type1
STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTB	2.824	Inactive	DFGin	BLAminus	in-in	in-out	NJV	Type1
STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTC	2.824	None	DFGin	BLAminus	in-in	in-none	NJV	Type1
STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTD	2.824	Active	DFGin	BLAminus	in-in	in-in	NJV	Type1

Protein kinases in complex with NJV

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	4	6OYTD

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTA	2.824	None	DFGin	BLAminus	in-in	in-none	NJV	Type1
Homo sapiens	STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTB	2.824	Inactive	DFGin	BLAminus	in-in	in-out	NJV	Type1
Homo sapiens	STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTC	2.824	None	DFGin	BLAminus	in-in	in-none	NJV	Type1
Homo sapiens	STE	MAP3K5	M3K5_HUMAN	Mitogen-activated protein kinase kinase kinase 5	6OYTD	2.824	Active	DFGin	BLAminus	in-in	in-in	NJV	Type1

Protein kinases in complex with NJV

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type