Protein kinases in complex with AV9 (Tivozanib)

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGout BBAminus 5 4ASEA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMD 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1
STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMG 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1
STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMA 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1.5_Front
STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMB 2.6 Inactive DFGout BBAminus out-out none-out AV9 Type1.5_Front
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4ASEA 1.83 Inactive DFGout BBAminus in-in out-in AV9 Type2

Protein kinases in complex with AV9

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGout BBAminus 5 4ASEA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMD 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1
Homo sapiens STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMG 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1
Homo sapiens STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMA 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1.5_Front
Homo sapiens STE SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 8BEMB 2.6 Inactive DFGout BBAminus out-out none-out AV9 Type1.5_Front
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4ASEA 1.83 Inactive DFGout BBAminus in-in out-in AV9 Type2

Protein kinases in complex with AV9

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type