Ligand: 8ET

Total number of chains: 1
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 5MZLA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK PIM1 PIM1_HUMAN 5MZL 1.955 Active DFGin‑BLAminus in-in in-in 8ET Type1 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1

Ligand: 8ET

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 5N1FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_CRIGR 5N1F 1.12 Inactive DFGin‑BLAminus in-in in-out 8ET Type1 12 - 351 0 X11,X140,X198,X339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CAMK PIM1 PIM1_HUMAN 5MZL 1.955 Active DFGin‑BLAminus in-in in-in 8ET Type1 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1 Homo sapiens

Ligand: 8ET

Total number of chains: 1
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 5N1FA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_CRIGR 5N1F 1.12 Inactive DFGin‑BLAminus in-in in-out 8ET Type1 12 - 351 0 X11,X140,X198,X339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus