Protein kinases in complex with 3E8 (Tepotinib)

Total number of genes: 1
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLBplus 6 4R1VA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AU3A 2.26 Inactive DFGin BLBplus out-out out-out 3E8 Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AU3B 2.26 Inactive DFGin BLBplus out-out out-out 3E8 Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AU5A 2.72 Inactive DFGin BLBplus out-out out-in 3E8 Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AW1A 2.14 Inactive DFGin BLBplus out-out out-in 3E8 Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AW1B 2.14 Inactive DFGin BLBplus out-out out-in 3E8 Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 4R1VA 1.2 Inactive DFGin BLBplus out-out out-in 3E8 Type1

Protein kinases in complex with 3E8

Total number of genes: 1
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLBplus 6 4R1VA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AU3A 2.26 Inactive DFGin BLBplus out-out out-out 3E8 Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AU3B 2.26 Inactive DFGin BLBplus out-out out-out 3E8 Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AU5A 2.72 Inactive DFGin BLBplus out-out out-in 3E8 Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AW1A 2.14 Inactive DFGin BLBplus out-out out-in 3E8 Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8AW1B 2.14 Inactive DFGin BLBplus out-out out-in 3E8 Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 4R1VA 1.2 Inactive DFGin BLBplus out-out out-in 3E8 Type1

Protein kinases in complex with 3E8

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type