VRK2 (Serine/threonine-protein kinase VRK2)

Group: CK1
Uniprot: VRK2_HUMAN
Domain boundary: 29 - 315


Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 6 AF-Q86Y07-K1A
DFGin ABAminus 1 5UU1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
5UU1A 2.0 Inactive DFGin ABAminus in-in in-in 7DZ Type1.5_Back 14 - 328 None None 0
AF-Q86Y07-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 21 - 323 None None 0
2V62A 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand 15 - 330 None None 0
2V62B 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand 15 - 330 None None 0
8Q1ZA 1.85 Active DFGin BLAminus in-in in-in IKD Type1 15 - 330 None None 0
6NCGA 2.45 None DFGin BLAminus in-none in-in KJD Type1.5_Back 14 - 326 None None 0
6NCGB 2.45 Inactive DFGin BLAminus in-out in-in KJD Type1.5_Back 16 - 326 None None 15

VRK2 (Serine/threonine-protein kinase VRK2)

Group: CK1
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 6 AF-Q86Y07-K1A
DFGin ABAminus 1 5UU1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens VRK2_HUMAN 5UU1A 2.0 Inactive DFGin ABAminus in-in in-in 7DZ Type1.5_Back 14 - 328 None None 0
Homo sapiens VRK2_HUMAN AF-Q86Y07-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 21 - 323 None None 0
Homo sapiens VRK2_HUMAN 2V62A 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand 15 - 330 None None 0
Homo sapiens VRK2_HUMAN 2V62B 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand 15 - 330 None None 0
Homo sapiens VRK2_HUMAN 8Q1ZA 1.85 Active DFGin BLAminus in-in in-in IKD Type1 15 - 330 None None 0
Homo sapiens VRK2_HUMAN 6NCGA 2.45 None DFGin BLAminus in-none in-in KJD Type1.5_Back 14 - 326 None None 0
Homo sapiens VRK2_HUMAN 6NCGB 2.45 Inactive DFGin BLAminus in-out in-in KJD Type1.5_Back 16 - 326 None None 15

VRK2 (Serine/threonine-protein kinase VRK2)

No non-human structures known.