TNNI3K (Serine/threonine-protein kinase TNNI3K)

Group: TKL
Uniprot: TNI3K_HUMAN
Domain boundary: 463 - 721


Total number of chains: 21
Spatial Dihedral Chains Representative
DFGin BLAminus 13 AF-Q59H18-K1A
DFGout BBAminus 8 7MGJA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q59H18-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 455 - 729 None None 0
4YFFA 3.07 None DFGin BLAminus in-in in-none 4CV Type1 445 - 726 None None 11
4YFFB 3.07 None DFGin BLAminus in-in in-none 4CV Type1 445 - 726 None None 12
4YFFC 3.07 Inactive DFGin BLAminus in-in in-out 4CV Type1 452 - 725 None None 8
4YFFD 3.07 Inactive DFGin BLAminus in-in in-out 4CV Type1 452 - 726 None None 10
6B5JA 2.97 Inactive DFGin BLAminus in-in in-out CV4 Type1 445 - 726 None None 10
6B5JB 2.97 None DFGin BLAminus in-in in-none CV4 Type1 445 - 726 None None 12
6B5JC 2.97 Inactive DFGin BLAminus in-in in-out CV4 Type1 451 - 726 None None 7
6B5JD 2.97 Inactive DFGin BLAminus in-in in-out CV4 Type1 452 - 726 None None 10
4YFIA 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 441 - 726 None None 11
4YFIB 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 451 - 729 None None 10
4YFIC 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 441 - 726 None None 10
4YFID 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 451 - 729 None None 10
7MGKA 3.1 Inactive DFGout BBAminus in-in none-out ZGD Type2 444 - 726 None None 16
7MGKB 3.1 Inactive DFGout BBAminus in-in none-out ZGD Type2 444 - 727 None None 16
7MGKC 3.1 Inactive DFGout BBAminus in-in none-none ZGD Type2 445 - 726 None None 16
7MGKD 3.1 Inactive DFGout BBAminus in-in none-out ZGD Type2 444 - 727 None None 14
7MGJA 2.95 Inactive DFGout BBAminus in-in none-out ZFS Type2 445 - 726 None None 16
7MGJB 2.95 Inactive DFGout BBAminus in-in none-out ZFS Type2 445 - 726 None None 15
7MGJC 2.95 Inactive DFGout BBAminus in-in none-none ZFS Type2 445 - 726 None None 16
7MGJD 2.95 Inactive DFGout BBAminus in-in none-out ZFS Type2 445 - 726 None None 14

TNNI3K (Serine/threonine-protein kinase TNNI3K)

Group: TKL
Total number of chains: 21
Spatial Dihedral Chains Representative
DFGin BLAminus 13 AF-Q59H18-K1A
DFGout BBAminus 8 7MGJA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens TNI3K_HUMAN AF-Q59H18-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 455 - 729 None None 0
Homo sapiens TNI3K_HUMAN 4YFFA 3.07 None DFGin BLAminus in-in in-none 4CV Type1 445 - 726 None None 11
Homo sapiens TNI3K_HUMAN 4YFFB 3.07 None DFGin BLAminus in-in in-none 4CV Type1 445 - 726 None None 12
Homo sapiens TNI3K_HUMAN 4YFFC 3.07 Inactive DFGin BLAminus in-in in-out 4CV Type1 452 - 725 None None 8
Homo sapiens TNI3K_HUMAN 4YFFD 3.07 Inactive DFGin BLAminus in-in in-out 4CV Type1 452 - 726 None None 10
Homo sapiens TNI3K_HUMAN 6B5JA 2.97 Inactive DFGin BLAminus in-in in-out CV4 Type1 445 - 726 None None 10
Homo sapiens TNI3K_HUMAN 6B5JB 2.97 None DFGin BLAminus in-in in-none CV4 Type1 445 - 726 None None 12
Homo sapiens TNI3K_HUMAN 6B5JC 2.97 Inactive DFGin BLAminus in-in in-out CV4 Type1 451 - 726 None None 7
Homo sapiens TNI3K_HUMAN 6B5JD 2.97 Inactive DFGin BLAminus in-in in-out CV4 Type1 452 - 726 None None 10
Homo sapiens TNI3K_HUMAN 4YFIA 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 441 - 726 None None 11
Homo sapiens TNI3K_HUMAN 4YFIB 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 451 - 729 None None 10
Homo sapiens TNI3K_HUMAN 4YFIC 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 441 - 726 None None 10
Homo sapiens TNI3K_HUMAN 4YFID 2.7 Inactive DFGin BLAminus in-in in-out 4CW Type1 451 - 729 None None 10
Homo sapiens TNI3K_HUMAN 7MGKA 3.1 Inactive DFGout BBAminus in-in none-out ZGD Type2 444 - 726 None None 16
Homo sapiens TNI3K_HUMAN 7MGKB 3.1 Inactive DFGout BBAminus in-in none-out ZGD Type2 444 - 727 None None 16
Homo sapiens TNI3K_HUMAN 7MGKC 3.1 Inactive DFGout BBAminus in-in none-none ZGD Type2 445 - 726 None None 16
Homo sapiens TNI3K_HUMAN 7MGKD 3.1 Inactive DFGout BBAminus in-in none-out ZGD Type2 444 - 727 None None 14
Homo sapiens TNI3K_HUMAN 7MGJA 2.95 Inactive DFGout BBAminus in-in none-out ZFS Type2 445 - 726 None None 16
Homo sapiens TNI3K_HUMAN 7MGJB 2.95 Inactive DFGout BBAminus in-in none-out ZFS Type2 445 - 726 None None 15
Homo sapiens TNI3K_HUMAN 7MGJC 2.95 Inactive DFGout BBAminus in-in none-none ZFS Type2 445 - 726 None None 16
Homo sapiens TNI3K_HUMAN 7MGJD 2.95 Inactive DFGout BBAminus in-in none-out ZFS Type2 445 - 726 None None 14

TNNI3K (Serine/threonine-protein kinase TNNI3K)

No non-human structures known.