RPS6KA1 (Ribosomal protein S6 kinase alpha-1)

RPS6KA1 has two kinase domains in its sequence, labeled here as RPS6KA1-1 and RPS6KA1-2. Structures with both domains are given in the last table and labeled as RPS6KA1-12.
Domain_1: RPS6KA1-1
Group: AGC
Example Uniprot: KS6A1_HUMAN
Domain boundary: 62 - 321

Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q15418-K1A
DFGin BLAplus 1 8XOVA
DFGin BLBplus 3 2Z7RA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment

Database table as tsv
Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KS6A1_HUMAN AF-Q15418-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 54 - 329 None None 0
Homo sapiens KS6A1_HUMAN 8XOVA 2.55 Inactive DFGin BLAplus out-out out-out ANP Type1 56 - 340 None None 9
Homo sapiens KS6A1_HUMAN 2Z7QA 2.0 Inactive DFGin BLBplus none-none out-out ACP Type1 56 - 340 None None 12
Homo sapiens KS6A1_HUMAN 2Z7RA 2.0 Inactive DFGin BLBplus none-none out-out STU Type1 53 - 340 None None 12
Homo sapiens KS6A1_HUMAN 2Z7SA 2.1 Inactive DFGin BLBplus none-none out-out P01 Type1 56 - 340 None None 12

RPS6KA1 (Ribosomal protein S6 kinase alpha-1)

Domain_2: RPS6KA1-2
Group: CAMK
Example Uniprot: KS6A1_HUMAN
Domain boundary: 418 - 675

Total number of chains in: 9
Spatial Dihedral Chains Representative
DFGin BLAminus 5 AF-Q15418-K2A
DFGin ABAminus 4 2WNTB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment

Database table as tsv
Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KS6A1_HUMAN 2WNTA 2.4 Inactive DFGin ABAminus in-in in-out No_ligand No_ligand 416 - 708 None None 7
Homo sapiens KS6A1_HUMAN 2WNTB 2.4 Inactive DFGin ABAminus in-in in-out No_ligand No_ligand 415 - 709 None None 8
Homo sapiens KS6A1_HUMAN 3RNYA 2.7 Inactive DFGin ABAminus in-in in-out No_ligand No_ligand 418 - 707 None None 6
Homo sapiens KS6A1_HUMAN 3RNYB 2.7 Inactive DFGin ABAminus in-in in-out No_ligand No_ligand 419 - 708 None None 8
Homo sapiens KS6A1_HUMAN AF-Q15418-K2A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 410 - 683 None None 0
Homo sapiens KS6A1_HUMAN 8WF4A 2.65 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 416 - 708 None None 5
Homo sapiens KS6A1_HUMAN 8WF4B 2.65 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 415 - 708 None None 4
Homo sapiens KS6A1_HUMAN 4NIFA 2.15 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 413 - 728 None None 3
Homo sapiens KS6A1_HUMAN 4NIFD 2.15 None DFGin BLAminus in-in in-none No_ligand No_ligand 413 - 728 None None 3

RPS6KA1 (Ribosomal protein S6 kinase alpha-1)

Domain_12: RPS6KA1-12
Total number of chains in: 0. Analysis of 2nd kinase domain given in table below.