IRAK3 (Interleukin-1 receptor-associated kinase 3)

Pseudokinase

Group: TKL

Uniprot: IRAK3_HUMAN

Domain boundary: 160 - 445

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	6RUUA
None	None	1	6RUUC

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
6RUUA	2.95	None	DFGin	BLAminus	in-out	in-none	No_ligand	No_ligand	153 - 450	None	None	10
6RUUB	2.95	Inactive	DFGin	BLAminus	in-out	in-out	No_ligand	No_ligand	152 - 452	None	None	8
6ZIWI	2.18	None	DFGin	BLAminus	in-out	in-none	AGS	Type1	153 - 451	None	None	19
6RUUC	2.95	Inactive	None	None	out-none	none-out	No_ligand	No_ligand	179 - 454	None	None	21

IRAK3 (Interleukin-1 receptor-associated kinase 3)

Pseudokinase

Group: TKL

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	6RUUA
None	None	1	6RUUC

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	IRAK3_HUMAN	6RUUA	2.95	None	DFGin	BLAminus	in-out	in-none	No_ligand	No_ligand	153 - 450	None	None	10
Homo sapiens	IRAK3_HUMAN	6RUUB	2.95	Inactive	DFGin	BLAminus	in-out	in-out	No_ligand	No_ligand	152 - 452	None	None	8
Homo sapiens	IRAK3_HUMAN	6ZIWI	2.18	None	DFGin	BLAminus	in-out	in-none	AGS	Type1	153 - 451	None	None	19
Homo sapiens	IRAK3_HUMAN	6RUUC	2.95	Inactive	None	None	out-none	none-out	No_ligand	No_ligand	179 - 454	None	None	21

IRAK3 (Interleukin-1 receptor-associated kinase 3)

No non-human structures known.