CDK1 (Cyclin-dependent kinase 1)

Group: CMGC
Uniprot: CDK1_HUMAN
Domain boundary: 4 - 287


Total number of chains: 19
Spatial Dihedral Chains Representative
DFGin BLAminus 10 AF-P06493-K1A
DFGin BLBplus 9 6GU7C
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P06493-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 1 - 295 None None 0
4YC3A 2.7 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 1 - 297 None None 3
7NJ0B 3.6 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 290 None X161 0
4Y72A 2.3 Inactive DFGin BLAminus in-in in-out LZ9 Type1 1 - 289 None None 0
5HQ0A 2.3 Inactive DFGin BLAminus in-in in-out LZ9 Type1 1 - 289 None None 0
5LQFA 2.06 Inactive DFGin BLAminus in-in in-out 4SP Type1 1 - 289 None None 5
5LQFD 2.06 None DFGin BLAminus in-in in-none 4SP Type1 1 - 289 None None 7
6GU2A 2.0 Inactive DFGin BLAminus out-out in-out F9Z Type1 1 - 294 None None 3
6GU3A 2.65 Inactive DFGin BLAminus in-in in-out FB8 Type1 1 - 289 None None 0
6GU4A 2.73 Inactive DFGin BLAminus in-in in-out FC8 Type1 1 - 289 None None 0
4YC6A 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
4YC6C 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
4YC6E 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
4YC6G 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
6GU7C 2.75 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 291 None None 0
6GU7E 2.75 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 292 None None 8
6GU7G 2.75 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 291 None None 8
6GU6A 2.33 Inactive DFGin BLBplus out-out out-out 1QK Type1 1 - 291 None None 3
6GU7A 2.75 Inactive DFGin BLBplus out-out out-out FB8 Type1 1 - 293 None None 9

CDK1 (Cyclin-dependent kinase 1)

Group: CMGC
Total number of chains: 19
Spatial Dihedral Chains Representative
DFGin BLAminus 10 AF-P06493-K1A
DFGin BLBplus 9 6GU7C
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens CDK1_HUMAN AF-P06493-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 1 - 295 None None 0
Homo sapiens CDK1_HUMAN 4YC3A 2.7 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 1 - 297 None None 3
Homo sapiens CDK1_HUMAN 7NJ0B 3.6 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 1 - 290 None X161 0
Homo sapiens CDK1_HUMAN 4Y72A 2.3 Inactive DFGin BLAminus in-in in-out LZ9 Type1 1 - 289 None None 0
Homo sapiens CDK1_HUMAN 5HQ0A 2.3 Inactive DFGin BLAminus in-in in-out LZ9 Type1 1 - 289 None None 0
Homo sapiens CDK1_HUMAN 5LQFA 2.06 Inactive DFGin BLAminus in-in in-out 4SP Type1 1 - 289 None None 5
Homo sapiens CDK1_HUMAN 5LQFD 2.06 None DFGin BLAminus in-in in-none 4SP Type1 1 - 289 None None 7
Homo sapiens CDK1_HUMAN 6GU2A 2.0 Inactive DFGin BLAminus out-out in-out F9Z Type1 1 - 294 None None 3
Homo sapiens CDK1_HUMAN 6GU3A 2.65 Inactive DFGin BLAminus in-in in-out FB8 Type1 1 - 289 None None 0
Homo sapiens CDK1_HUMAN 6GU4A 2.73 Inactive DFGin BLAminus in-in in-out FC8 Type1 1 - 289 None None 0
Homo sapiens CDK1_HUMAN 4YC6A 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
Homo sapiens CDK1_HUMAN 4YC6C 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
Homo sapiens CDK1_HUMAN 4YC6E 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
Homo sapiens CDK1_HUMAN 4YC6G 2.6 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 289 None None 4
Homo sapiens CDK1_HUMAN 6GU7C 2.75 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 291 None None 0
Homo sapiens CDK1_HUMAN 6GU7E 2.75 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 292 None None 8
Homo sapiens CDK1_HUMAN 6GU7G 2.75 Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 1 - 291 None None 8
Homo sapiens CDK1_HUMAN 6GU6A 2.33 Inactive DFGin BLBplus out-out out-out 1QK Type1 1 - 291 None None 3
Homo sapiens CDK1_HUMAN 6GU7A 2.75 Inactive DFGin BLBplus out-out out-out FB8 Type1 1 - 293 None None 9

CDK1 (Cyclin-dependent kinase 1)

No non-human structures known.