PDB: AF-Q12852 — TKL M3K12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q12852-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K1A Q12852 117 374 859.0 No_ligand No_ligand Active DFGin 6.4258 14.4038 BLAminus -135.37, 174.94 59.09, 75.76 -81.87, 15.15 290.24, 86.78 -63.45, -16.18 in-na in 9.0259 Saltbr-na 5.0805 HRD-in -74.58, -46.99 68.83, -6.59 na-in-in SNCaii in-in ActLoopNT-in 2.9293 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.29, 155.5 APE9-dihe-na 115.77, -178.15 APE8-dihe-in -101.06, 126.9 APE8-rot-in 306.9 APE67-dihe-in -65.79, -18.28 -46.31, -46.72 APE12-dist-in 8.8055 APE11-dist-in 11.076 APE10-dist-in 5.3824 APE9-dist-in 3.438 None None None AF2 -1.0 1.0 1.0 A 258.0 258.0 0 27 27 0 [[118, 372]] 1.0 AF-Q12852-K1 TKL_MAP3K12_HUMAN MAP3K123 8.4e-138 463.6 1.0 254.0 254.0 253 254 255 257 259 152 161 165 233 235 234 236.0 292 280 275 274 273 272 271 270 269 191 Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K3A Q12852 117 374 859.0 No_ligand No_ligand Active DFGin 6.2508 14.5575 BLAminus -140.65, -175.73 52.42, 68.88 -73.59, 9.91 294.28, 96.63 -59.3, -19.37 in-na in 9.0783 Saltbr-na 5.3305 HRD-in -74.8, -45.87 67.92, -9.13 na-in-in SNCaii in-in ActLoopNT-in 2.9232 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.36, 146.36 APE9-dihe-na 105.87, -173.52 APE8-dihe-in -105.9, 126.7 APE8-rot-in 310.93 APE67-dihe-in -64.79, -18.86 -50.97, -43.69 APE12-dist-in 8.6823 APE11-dist-in 11.2814 APE10-dist-in 5.4772 APE9-dist-in 3.635 None None None AF2 -1.0 1.0 1.0 A 258.0 258.0 0 27 27 0 [[118, 372]] 1.0 AF-Q12852-K3 TKL_MAP3K12_HUMAN MAP3K123 8.4e-138 463.6 1.0 254.0 254.0 253 254 255 257 259 152 161 165 233 235 234 236.0 292 280 275 274 273 272 271 270 269 191 Mitogen-activated protein kinase kinase kinase 12

PDB: AF-Q12852 — TKL M3K12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q12852-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K1A Q12852 117 374 859.0 No_ligand No_ligand Active DFGin 6.4258 14.4038 BLAminus -135.37, 174.94 59.09, 75.76 -81.87, 15.15 290.24, 86.78 -63.45, -16.18 in-na in 9.0259 Saltbr-na 5.0805 HRD-in -74.58, -46.99 68.83, -6.59 na-in-in SNCaii in-in ActLoopNT-in 2.9293 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.29, 155.5 APE9-dihe-na 115.77, -178.15 APE8-dihe-in -101.06, 126.9 APE8-rot-in 306.9 APE67-dihe-in -65.79, -18.28 -46.31, -46.72 APE12-dist-in 8.8055 APE11-dist-in 11.076 APE10-dist-in 5.3824 APE9-dist-in 3.438 None None None AF2 -1.0 1.0 1.0 A 258.0 258.0 0 27 27 0 [[118, 372]] 1.0 AF-Q12852-K1 Homo sapiens TKL_MAP3K12_HUMAN MAP3K123 8.4e-138 463.6 1.0 254.0 254.0 253 254 255 257 259 152 161 165 233 235 234 236.0 292 280 275 274 273 272 271 270 269 191 Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K3A Q12852 117 374 859.0 No_ligand No_ligand Active DFGin 6.2508 14.5575 BLAminus -140.65, -175.73 52.42, 68.88 -73.59, 9.91 294.28, 96.63 -59.3, -19.37 in-na in 9.0783 Saltbr-na 5.3305 HRD-in -74.8, -45.87 67.92, -9.13 na-in-in SNCaii in-in ActLoopNT-in 2.9232 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -149.36, 146.36 APE9-dihe-na 105.87, -173.52 APE8-dihe-in -105.9, 126.7 APE8-rot-in 310.93 APE67-dihe-in -64.79, -18.86 -50.97, -43.69 APE12-dist-in 8.6823 APE11-dist-in 11.2814 APE10-dist-in 5.4772 APE9-dist-in 3.635 None None None AF2 -1.0 1.0 1.0 A 258.0 258.0 0 27 27 0 [[118, 372]] 1.0 AF-Q12852-K3 Homo sapiens TKL_MAP3K12_HUMAN MAP3K123 8.4e-138 463.6 1.0 254.0 254.0 253 254 255 257 259 152 161 165 233 235 234 236.0 292 280 275 274 273 272 271 270 269 191 Mitogen-activated protein kinase kinase kinase 12

PDB: AF-Q12852 — TKL M3K12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name