PDB: 9TYG — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9TYGB
DFGin BLBplus 1 50.0% 9TYGA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 9TYGB P28482 11 360 360.0 ADP:60401 ATPlike Inactive DFGin 6.898 16.594 BLAminus DFGAsp-rot-in -153.9489, 169.8461 60.305, 62.5564 188.7494, 11.7607 -84.7158, 20.9355 286.4073, 71.6173 -61.6844, -40.6601 out-out out 10.248 Saltbr-out 4.819 HRD-out -85.0203, 75.2202 -56.6891, 154.9387 out-in-out SNCoio in-out ActLoopNT-in 2.948 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iioo APE10-dihe-na -145.1786, 163.3978 APE9-dihe-na 75.6785, -7.8231 APE8-dihe-out 178.3832, 160.9059 APE8-rot-out 185.4878 APE67-dihe-in -76.8557, -21.7295 -135.6775, 12.5655 APE12-dist-in 10.438 APE11-dist-in 9.444 APE10-dist-out 11.133 APE9-dist-out 12.483 T185V None None EM 2.9 999.0 999.0 B 363 350 0 0 0 0 [[25, 313]] 1.0 9tyg CMGC_MAPK1_HUMAN CMGC 5.3e-85 291.3 1 301 301 166 167 168 170 172 54 71 75 146 148 147 149 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYGA Q02750 441 382 393.0 ADP:60501 ATPlike Inactive DFGin 5.266 14.468 BLBplus DFGAsp-rot-out -158.8103, 165.2981 54.981, 56.0505 261.7127, -27.3706 -103.6778, 164.0681 54.7406, 100.1114 61.5666, -134.518 out-out out 17.414 Saltbr-out 19.556 HRD-out -87.1082, 129.9339 -104.0708, -20.4742 out-out-out SNCooo out-out ActLoopNT-out 8.316 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -63.1406, -35.8636 APE9-dihe-na -146.2959, 161.9945 APE8-dihe-out 55.045, 22.5732 APE8-rot-out 62.5758 APE67-dihe-in -65.7118, -13.4295 -96.3728, 15.6742 APE12-dist-out 20.746 APE11-dist-out 20.695 APE10-dist-out 25.288 APE9-dist-out 15.755 S218D,S222D None None EM 2.9 999.0 999.0 A 405 280 41 0 0 0 [[68, 361]] 1.0 9tyg STE_MAP2K1_HUMAN STE 7.9e-97 329.8 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYG — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9TYGB
DFGin BLBplus 1 50.0% 9TYGA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 9TYGB P28482 11 360 360.0 ADP:60401 ATPlike Inactive DFGin 6.898 16.594 BLAminus DFGAsp-rot-in -153.9489, 169.8461 60.305, 62.5564 188.7494, 11.7607 -84.7158, 20.9355 286.4073, 71.6173 -61.6844, -40.6601 out-out out 10.248 Saltbr-out 4.819 HRD-out -85.0203, 75.2202 -56.6891, 154.9387 out-in-out SNCoio in-out ActLoopNT-in 2.948 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iioo APE10-dihe-na -145.1786, 163.3978 APE9-dihe-na 75.6785, -7.8231 APE8-dihe-out 178.3832, 160.9059 APE8-rot-out 185.4878 APE67-dihe-in -76.8557, -21.7295 -135.6775, 12.5655 APE12-dist-in 10.438 APE11-dist-in 9.444 APE10-dist-out 11.133 APE9-dist-out 12.483 T185V None None EM 2.9 999.0 999.0 B 363 350 0 0 0 0 [[25, 313]] 1.0 9tyg Homo sapiens CMGC_MAPK1_HUMAN CMGC 5.3e-85 291.3 1 301 301 166 167 168 170 172 54 71 75 146 148 147 149 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYGA Q02750 441 382 393.0 ADP:60501 ATPlike Inactive DFGin 5.266 14.468 BLBplus DFGAsp-rot-out -158.8103, 165.2981 54.981, 56.0505 261.7127, -27.3706 -103.6778, 164.0681 54.7406, 100.1114 61.5666, -134.518 out-out out 17.414 Saltbr-out 19.556 HRD-out -87.1082, 129.9339 -104.0708, -20.4742 out-out-out SNCooo out-out ActLoopNT-out 8.316 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -63.1406, -35.8636 APE9-dihe-na -146.2959, 161.9945 APE8-dihe-out 55.045, 22.5732 APE8-rot-out 62.5758 APE67-dihe-in -65.7118, -13.4295 -96.3728, 15.6742 APE12-dist-out 20.746 APE11-dist-out 20.695 APE10-dist-out 25.288 APE9-dist-out 15.755 S218D,S222D None None EM 2.9 999.0 999.0 A 405 280 41 0 0 0 [[68, 361]] 1.0 9tyg Homo sapiens STE_MAP2K1_HUMAN STE 7.9e-97 329.8 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYG — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name