Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KA | Q9NWZ3 | 162 | 460 | 460.0 | A1JDQ:501 | Type1 | Active | DFGin | 6.926 | 14.084 | BLAminus | -126.64, 177.21 | 56.19, 79.08 | -95.18, 26.45 | 305.03, 89.52 | -65.57, -28.51 | in-in | in | 8.906 | Saltbr-in | 3.167 | HRD-in | -66.88, -49.66 | 78.32, -6.79 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.873 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -122.84, 161.94 | APE9-dihe-na | 133.27, -170.49 | APE8-dihe-in | -114.57, 114.37 | APE8-rot-in | 305.97 | APE67-dihe-in | -63.05, -13.23 | -41.26, -51.52 | APE12-dist-in | 10.133 | APE11-dist-in | 11.553 | APE10-dist-in | 6.178 | APE9-dist-in | 3.667 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | A | 308 | 286 | 13 | 0 | 0 | 7 | [[183, 456]] | 1.0 | 9r9k | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KB | Q9NWZ3 | 158 | 460 | 460.0 | A1JDQ:501 | Type1 | Active | DFGin | 7.054 | 14.009 | BLAminus | -121.37, 179.62 | 54.87, 78.76 | -94.27, 23.12 | 304.61, 89.05 | -66.48, -26.41 | in-in | in | 9.139 | Saltbr-in | 3.574 | HRD-in | -67.81, -49.8 | 79.17, -8.08 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.878 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -121.42, 161.33 | APE9-dihe-na | 132.97, -172.93 | APE8-dihe-in | -114.32, 113.72 | APE8-rot-in | 306.88 | APE67-dihe-in | -62.56, -13.28 | -40.03, -52.35 | APE12-dist-in | 10.16 | APE11-dist-in | 11.517 | APE10-dist-in | 6.14 | APE9-dist-in | 3.728 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | B | 308 | 290 | 13 | 0 | 0 | 7 | [[183, 456]] | 1.0 | 9r9k | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KD | Q9NWZ3 | 164 | 459 | 460.0 | A1JDQ:501 | Type1 | Inactive | DFGin | 7.263 | 13.909 | BLAminus | -127.82, -173.62 | 51.62, 79.16 | -94.28, 25.38 | 306.25, 90.36 | -67.69, -32.97 | in-out | in | 9.219 | Saltbr-out | 3.686 | HRD-in | -67.18, -49.93 | 79.82, -9.59 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.86 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -122.33, 161.69 | APE9-dihe-na | 131.99, -171.77 | APE8-dihe-in | -113.49, 115.43 | APE8-rot-in | 306.97 | APE67-dihe-in | -64.18, -12.29 | -42.85, -50.18 | APE12-dist-in | 10.229 | APE11-dist-in | 11.661 | APE10-dist-in | 6.258 | APE9-dist-in | 3.695 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | D | 308 | 287 | 9 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 9r9k | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KC | Q9NWZ3 | 164 | 460 | 460.0 | A1JDQ:501 | Type1 | Inactive | DFGin | 5.427 | 13.7 | BLAplus | -121.4, 174.92 | 52.96, 52.1 | -113.08, 22.09 | 63.11, 100.55 | -82.15, -34.43 | in-in | in | 9.004 | Saltbr-in | 3.564 | HRD-in | -66.7, -51.75 | 79.98, -9.1 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.877 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iioi | APE10-dihe-na | -121.02, 159.56 | APE9-dihe-na | 135.26, -175.03 | APE8-dihe-in | -112.94, 115.11 | APE8-rot-in | 304.94 | APE67-dihe-in | -64.76, -11.9 | -41.19, -51.22 | APE12-dist-in | 11.501 | APE11-dist-in | 13.588 | APE10-dist-out | 8.35 | APE9-dist-in | 3.707 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | C | 308 | 287 | 10 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 9r9k | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KA | Q9NWZ3 | 162 | 460 | 460.0 | A1JDQ:501 | Type1 | Active | DFGin | 6.926 | 14.084 | BLAminus | -126.64, 177.21 | 56.19, 79.08 | -95.18, 26.45 | 305.03, 89.52 | -65.57, -28.51 | in-in | in | 8.906 | Saltbr-in | 3.167 | HRD-in | -66.88, -49.66 | 78.32, -6.79 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.873 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -122.84, 161.94 | APE9-dihe-na | 133.27, -170.49 | APE8-dihe-in | -114.57, 114.37 | APE8-rot-in | 305.97 | APE67-dihe-in | -63.05, -13.23 | -41.26, -51.52 | APE12-dist-in | 10.133 | APE11-dist-in | 11.553 | APE10-dist-in | 6.178 | APE9-dist-in | 3.667 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | A | 308 | 286 | 13 | 0 | 0 | 7 | [[183, 456]] | 1.0 | 9r9k | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KB | Q9NWZ3 | 158 | 460 | 460.0 | A1JDQ:501 | Type1 | Active | DFGin | 7.054 | 14.009 | BLAminus | -121.37, 179.62 | 54.87, 78.76 | -94.27, 23.12 | 304.61, 89.05 | -66.48, -26.41 | in-in | in | 9.139 | Saltbr-in | 3.574 | HRD-in | -67.81, -49.8 | 79.17, -8.08 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.878 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -121.42, 161.33 | APE9-dihe-na | 132.97, -172.93 | APE8-dihe-in | -114.32, 113.72 | APE8-rot-in | 306.88 | APE67-dihe-in | -62.56, -13.28 | -40.03, -52.35 | APE12-dist-in | 10.16 | APE11-dist-in | 11.517 | APE10-dist-in | 6.14 | APE9-dist-in | 3.728 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | B | 308 | 290 | 13 | 0 | 0 | 7 | [[183, 456]] | 1.0 | 9r9k | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KD | Q9NWZ3 | 164 | 459 | 460.0 | A1JDQ:501 | Type1 | Inactive | DFGin | 7.263 | 13.909 | BLAminus | -127.82, -173.62 | 51.62, 79.16 | -94.28, 25.38 | 306.25, 90.36 | -67.69, -32.97 | in-out | in | 9.219 | Saltbr-out | 3.686 | HRD-in | -67.18, -49.93 | 79.82, -9.59 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.86 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -122.33, 161.69 | APE9-dihe-na | 131.99, -171.77 | APE8-dihe-in | -113.49, 115.43 | APE8-rot-in | 306.97 | APE67-dihe-in | -64.18, -12.29 | -42.85, -50.18 | APE12-dist-in | 10.229 | APE11-dist-in | 11.661 | APE10-dist-in | 6.258 | APE9-dist-in | 3.695 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | D | 308 | 287 | 9 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 9r9k | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 9R9KC | Q9NWZ3 | 164 | 460 | 460.0 | A1JDQ:501 | Type1 | Inactive | DFGin | 5.427 | 13.7 | BLAplus | -121.4, 174.92 | 52.96, 52.1 | -113.08, 22.09 | 63.11, 100.55 | -82.15, -34.43 | in-in | in | 9.004 | Saltbr-in | 3.564 | HRD-in | -66.7, -51.75 | 79.98, -9.1 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.877 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iioi | APE10-dihe-na | -121.02, 159.56 | APE9-dihe-na | 135.26, -175.03 | APE8-dihe-in | -112.94, 115.11 | APE8-rot-in | 304.94 | APE67-dihe-in | -64.76, -11.9 | -41.19, -51.22 | APE12-dist-in | 11.501 | APE11-dist-in | 13.588 | APE10-dist-out | 8.35 | APE9-dist-in | 3.707 | None | TPO345,SEP346 | TPO345,SEP346 | XRAY | 1.87 | 0.216 | 0.242 | C | 308 | 287 | 10 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 9r9k | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|