9QEK

ROS1 (Proto-oncogene tyrosine-protein kinase ROS)
Group: TYR
Uniprot: ROS1_HUMAN
Organism: Homo sapiens
Domain boundary: 1945 - 2217
Resolu: 2.205

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-out none-out A1I6Z Type1 1934 - 2229 18
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1941       1951       1961       1971 
gSIENLPAFP REKLTLRLLL GSGafGEVYE GTAVDILgvG 
      1981       1991       2001       2011 
SGEIKVAVKT LKKGSTDQEK IEFLKEAHLM SKFNHPNILK 
      2021       2031       2041       2051 
QLGVCLLNEP QYIILELMEG RDLLTYLRKA RMATFYGPLL 
      2061       2071       2081       2091 
TLVDLVDLCV DISKGCVYLE RMHFIHRDLA ARNCLVSVKD 
      2101       2111       2121       2131 
YTSPRIVKIG DFglardiyk ndyyrkrgeg LLPVRWMAPE 
      2141       2151       2161       2171 
SLMDGIFTTQ SDVWSFGILI WEILTLGHQP YPAHSNLDVL 
      2181       2191       2201       2211 
NYVQTGGRLE PPRNCPDDLW NLMTQCWAQE PDQRPTFHRI 
      2221       2231 
QDQLQLFRNF FLNSIYKSrd e
Lower-case residues are disordered in structure.
Mutations: G2032R
Phosphorylation: None