PDB: 9MMS — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9MMSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9MMSB Q02750 63 380 393.0 AGS:701,LCJ:703 ATPlike,Type3 Inactive DFGin 6.8547 13.563 BLBplus -141.52, 164.23 63.42, 46.21 -99.5, 165.31 34.19, 90.42 -80.53, 73.26 out-out out 15.4077 Saltbr-out 15.7694 HRD-in -66.2, -52.71 70.98, -11.79 out-out-out SNCooo out-out ActLoopNT-out 8.8575 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -63.41, 150.0 APE9-dihe-na -102.92, -178.46 APE8-dihe-out -108.1, -35.69 APE8-rot-in 324.75 APE67-dihe-out -152.78, 143.47 -133.76, 175.52 APE12-dist-out 17.2823 APE11-dist-out 22.2166 APE10-dist-out 24.3527 APE9-dist-out 13.6751 S218A,S222A None None EM 3.3 999.0 999.0 B 415.0 278.0 40 26 26 0 [[68, 361]] 1.0 9mms STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9MMSA P04049 343 610 648.0 AGS:701 ATPlike Inactive DFGin 6.0432 13.4123 BLBplus -130.72, 176.22 57.09, 37.64 -95.88, 150.42 38.9, 90.55 70.15, -138.14 out-out out 13.239 Saltbr-out 11.9633 HRD-out -75.89, 77.72 -68.75, 167.65 out-out-out SNCooo out-out ActLoopNT-out 9.0132 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -153.3, 137.93 APE9-dihe-na 117.05, 178.36 APE8-dihe-in -66.7, 143.78 APE8-rot-in 289.18 APE67-dihe-in -66.49, -26.11 -89.17, -21.29 APE12-dist-out 15.1652 APE11-dist-out 14.8651 APE10-dist-out 10.7824 APE9-dist-out 8.09 Q156R,Y340D,Y341D,D587E None None EM 3.3 999.0 999.0 A 681.0 268.0 0 30 30 0 [[349, 608]] 1.0 9mms TKL_RAF1_HUMAN TKL 2e-80 276.3 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9MMS — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9MMSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9MMSB Q02750 63 380 393.0 AGS:701,LCJ:703 ATPlike,Type3 Inactive DFGin 6.8547 13.563 BLBplus -141.52, 164.23 63.42, 46.21 -99.5, 165.31 34.19, 90.42 -80.53, 73.26 out-out out 15.4077 Saltbr-out 15.7694 HRD-in -66.2, -52.71 70.98, -11.79 out-out-out SNCooo out-out ActLoopNT-out 8.8575 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -63.41, 150.0 APE9-dihe-na -102.92, -178.46 APE8-dihe-out -108.1, -35.69 APE8-rot-in 324.75 APE67-dihe-out -152.78, 143.47 -133.76, 175.52 APE12-dist-out 17.2823 APE11-dist-out 22.2166 APE10-dist-out 24.3527 APE9-dist-out 13.6751 S218A,S222A None None EM 3.3 999.0 999.0 B 415.0 278.0 40 26 26 0 [[68, 361]] 1.0 9mms Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9MMSA P04049 343 610 648.0 AGS:701 ATPlike Inactive DFGin 6.0432 13.4123 BLBplus -130.72, 176.22 57.09, 37.64 -95.88, 150.42 38.9, 90.55 70.15, -138.14 out-out out 13.239 Saltbr-out 11.9633 HRD-out -75.89, 77.72 -68.75, 167.65 out-out-out SNCooo out-out ActLoopNT-out 9.0132 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -153.3, 137.93 APE9-dihe-na 117.05, 178.36 APE8-dihe-in -66.7, 143.78 APE8-rot-in 289.18 APE67-dihe-in -66.49, -26.11 -89.17, -21.29 APE12-dist-out 15.1652 APE11-dist-out 14.8651 APE10-dist-out 10.7824 APE9-dist-out 8.09 Q156R,Y340D,Y341D,D587E None None EM 3.3 999.0 999.0 A 681.0 268.0 0 30 30 0 [[349, 608]] 1.0 9mms Homo sapiens TKL_RAF1_HUMAN TKL 2e-80 276.3 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9MMS — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name