9EP8

ROCK2 (Rho-associated protein kinase 2)
Group: AGC
Uniprot: ROCK2_HUMAN
Organism: Homo sapiens
Domain boundary: 92 - 354
Resolu: 2.63

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out A1H6L Type1 22 - 417 2
B None DFGin BLAminus in-in in-none A1H6L Type1 24 - 417 12
C None DFGin BLAminus in-in in-none A1H6L Type1 24 - 417 12
D Inactive DFGin BLAminus in-in in-out A1H6L Type1 22 - 417 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        25         35         45         55 
gaagdgAGAS RQRKLEALIR DPRSPINVES LLDGLNSLVL 
        65         75         85         95 
DLDFPALRKN KNIDNFLNRY EKIVKKIRGL QMKAEDYDVV 
       105        115        125        135 
KVIGRGAFGE VQLVRHKASQ KVYAMKLLSK FEMIKRSDSA 
       145        155        165        175 
FFWEERDIMA FANSPWVVQL FYAFQDDRYL YMVMEYMPGG 
       185        195        205        215 
DLVNLMSNYD VPEKWAKFYT AEVVLALDAI HSMGLIHRDV 
       225        235        245        255 
KPDNMLLDKH GHLKLADFGT CMKMDETGMV HcdTAVGTPD 
       265        275        285        295 
YISPEVLKSQ ggdGFYGREC DWWSVGVFLY EMLVGDTPFY 
       305        315        325        335 
ADSLVGTYSK IMDHKNSLCF PEDAEISKHA KNLICAFLTD 
       345        355        365        375 
REVRLGRNGV EEIRQHPFFK NDQWHWDNIR ETAAPVVPEL 
       385        395        405        415 
SSDIDSSNFD DIEddkgdVE TFPIPKAFVG NQLPFIGFTY 

YR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None