PDB: 9AY7 — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9AY7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9AY7B Q02750 33 383 393.0 A1AHE:401,ANP:402 Type1,ATPlike Inactive DFGin 6.1312 14.2675 BLBplus -154.96, 169.08 61.0, 36.72 -91.6, 162.02 49.73, 81.71 -77.61, 77.19 out-out out 15.5132 Saltbr-out 15.4022 HRD-in -75.89, -55.94 83.29, -11.88 out-out-out SNCooo out-out ActLoopNT-out 9.5756 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -66.62, 136.57 APE9-dihe-na -89.93, -175.43 APE8-dihe-out -113.57, -10.62 APE8-rot-out 51.26 APE67-dihe-out -146.5, 144.85 -157.42, 170.13 APE12-dist-out 17.3436 APE11-dist-out 22.1142 APE10-dist-out 24.2068 APE9-dist-out 13.7295 S218A,S222A None None XRAY 2.41 0.203 0.236 B 394.0 322.0 29 26 26 0 [[68, 361]] 1.0 9ay7 STE_MAP2K1_HUMAN STE 1.1e-96 329.3 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9AY7A P04049 343 612 648.0 ANP:701 ATPlike Inactive DFGin 5.8053 13.462 BLBplus -133.55, 174.37 58.47, 38.44 -90.49, 142.18 44.05, 90.72 78.29, -134.9 out-out out 14.0699 Saltbr-out 12.7376 HRD-in -73.02, -44.7 76.86, -25.12 out-out-out SNCooo out-out ActLoopNT-out 9.1822 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -145.48, 130.61 APE9-dihe-na 129.03, -169.57 APE8-dihe-in -79.63, 137.79 APE8-rot-in 302.79 APE67-dihe-in -63.4, -34.24 -69.33, -38.68 APE12-dist-out 15.2361 APE11-dist-out 15.0562 APE10-dist-out 10.6236 APE9-dist-out 6.3059 Y340D,Y341D None None XRAY 2.41 0.203 0.236 A 280.0 260.0 10 30 24 6 [[349, 608]] 1.0 9ay7 TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9AY7 — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9AY7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9AY7B Q02750 33 383 393.0 A1AHE:401,ANP:402 Type1,ATPlike Inactive DFGin 6.1312 14.2675 BLBplus -154.96, 169.08 61.0, 36.72 -91.6, 162.02 49.73, 81.71 -77.61, 77.19 out-out out 15.5132 Saltbr-out 15.4022 HRD-in -75.89, -55.94 83.29, -11.88 out-out-out SNCooo out-out ActLoopNT-out 9.5756 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -66.62, 136.57 APE9-dihe-na -89.93, -175.43 APE8-dihe-out -113.57, -10.62 APE8-rot-out 51.26 APE67-dihe-out -146.5, 144.85 -157.42, 170.13 APE12-dist-out 17.3436 APE11-dist-out 22.1142 APE10-dist-out 24.2068 APE9-dist-out 13.7295 S218A,S222A None None XRAY 2.41 0.203 0.236 B 394.0 322.0 29 26 26 0 [[68, 361]] 1.0 9ay7 Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.3 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9AY7A P04049 343 612 648.0 ANP:701 ATPlike Inactive DFGin 5.8053 13.462 BLBplus -133.55, 174.37 58.47, 38.44 -90.49, 142.18 44.05, 90.72 78.29, -134.9 out-out out 14.0699 Saltbr-out 12.7376 HRD-in -73.02, -44.7 76.86, -25.12 out-out-out SNCooo out-out ActLoopNT-out 9.1822 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -145.48, 130.61 APE9-dihe-na 129.03, -169.57 APE8-dihe-in -79.63, 137.79 APE8-rot-in 302.79 APE67-dihe-in -63.4, -34.24 -69.33, -38.68 APE12-dist-out 15.2361 APE11-dist-out 15.0562 APE10-dist-out 10.6236 APE9-dist-out 6.3059 Y340D,Y341D None None XRAY 2.41 0.203 0.236 A 280.0 260.0 10 30 24 6 [[349, 608]] 1.0 9ay7 Homo sapiens TKL_RAF1_HUMAN TKL 2.6e-81 279.0 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9AY7 — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name