| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYA | P51812 | 58 | 358 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 13.2049 | 7.3468 | None | -84.69, 175.04 | -98.49, -2.97 | -56.06, -41.49 | 288.51, 111.93 | -88.04, -1.58 | out-out | out | 13.584 | Saltbr-out | 12.4908 | HRD-out | -102.98, 108.87 | -62.66, -66.03 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.2899 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooo | APE10-dihe-na | -171.34, 174.53 | APE9-dihe-na | 132.9, 150.52 | APE8-dihe-in | -54.44, 119.7 | APE8-rot-in | 325.6 | APE67-dihe-in | -67.51, -35.24 | -72.39, -24.23 | APE12-dist-none | 999.0 | APE11-dist-out | 15.3012 | APE10-dist-out | 13.362 | APE9-dist-out | 6.3968 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | A | 320.0 | 289.0 | 12 | 28 | 19 | 9 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYB | P51812 | 59 | 358 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.4755 | 7.6225 | None | -79.21, 172.69 | -104.74, 14.38 | -72.96, -37.65 | 288.72, 121.74 | -83.1, -14.53 | out-out | out | 13.02 | Saltbr-out | 10.2513 | HRD-out | -85.11, 105.26 | -64.66, -55.07 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1807 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -141.21, 158.45 | APE9-dihe-na | 119.59, 160.83 | APE8-dihe-in | -64.8, 132.56 | APE8-rot-out | 38.16 | APE67-dihe-in | -76.3, -33.52 | -81.38, -10.91 | APE12-dist-none | 999.0 | APE11-dist-out | 15.9119 | APE10-dist-out | 12.4271 | APE9-dist-out | 6.3691 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | B | 320.0 | 277.0 | 23 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYC | P51812 | 61 | 358 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 13.0072 | 7.4047 | None | -74.08, -176.12 | -117.42, 16.75 | -70.92, -31.59 | 288.86, 115.13 | -89.42, -33.94 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -99.11, 116.77 | -79.3, -60.22 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.1388 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooo | APE10-dihe-na | -154.86, 91.8 | APE9-dihe-na | -163.03, 159.53 | APE8-dihe-in | -69.77, 116.03 | APE8-rot-in | 309.84 | APE67-dihe-in | -63.05, -25.35 | -70.36, -29.8 | APE12-dist-none | 999.0 | APE11-dist-out | 15.6924 | APE10-dist-out | 13.2566 | APE9-dist-out | 6.1853 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | C | 320.0 | 272.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYD | P51812 | 63 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.6801 | 7.7179 | None | -85.23, 171.03 | -99.91, 5.18 | -66.56, -47.9 | 288.97, 119.73 | -68.87, -42.49 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -108.97, 107.04 | -79.62, 147.57 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.0043 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -160.66, -177.37 | APE9-dihe-na | 101.82, 157.81 | APE8-dihe-in | -62.84, 132.59 | APE8-rot-out | 47.92 | APE67-dihe-in | -68.43, -26.54 | -77.35, -22.1 | APE12-dist-none | 999.0 | APE11-dist-out | 16.0048 | APE10-dist-out | 13.6407 | APE9-dist-out | 7.2804 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | D | 320.0 | 260.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYE | P51812 | 64 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.8137 | 7.7319 | None | -79.79, 173.69 | -104.44, 5.05 | -67.56, -37.65 | 296.33, 117.93 | -76.73, -31.97 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -107.95, 111.24 | -79.69, -31.85 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.217 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooi | APE10-dihe-na | -171.13, 156.06 | APE9-dihe-na | 118.15, 155.77 | APE8-dihe-in | -55.33, 128.86 | APE8-rot-out | 36.52 | APE67-dihe-in | -70.55, -22.72 | -79.46, -18.88 | APE12-dist-none | 999.0 | APE11-dist-out | 16.5561 | APE10-dist-out | 12.7625 | APE9-dist-in | 5.5786 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | E | 320.0 | 261.0 | 24 | 28 | 19 | 9 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYF | P51812 | 63 | 345 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.7435 | 7.4714 | None | -95.59, -178.42 | -108.18, 9.34 | -70.41, -40.72 | 293.14, 115.72 | -77.9, -28.8 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -100.4, 115.65 | -68.34, -48.2 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.1559 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -160.1, 173.9 | APE9-dihe-na | 114.4, 160.81 | APE8-dihe-in | -56.13, 119.9 | APE8-rot-out | 41.37 | APE67-dihe-in | -71.03, -16.28 | -73.87, -18.19 | APE12-dist-none | 999.0 | APE11-dist-out | 15.3915 | APE10-dist-out | 13.539 | APE9-dist-out | 6.404 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | F | 320.0 | 255.0 | 28 | 28 | 17 | 11 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYG | P51812 | 59 | 346 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.937 | 7.2256 | None | -78.16, 176.02 | -98.19, 0.09 | -62.25, -40.75 | 291.8, 111.06 | -81.64, -19.61 | in-out | in | 7.8808 | Saltbr-out | 5.486 | HRD-out | -91.07, 110.45 | -88.21, -3.19 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1639 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooi | APE10-dihe-na | -71.01, 158.33 | APE9-dihe-na | 129.65, 145.56 | APE8-dihe-in | -72.78, 126.88 | APE8-rot-in | 303.8 | APE67-dihe-in | -65.24, -40.51 | -67.91, -29.47 | APE12-dist-none | 999.0 | APE11-dist-out | 16.1451 | APE10-dist-out | 12.0692 | APE9-dist-in | 4.6444 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | G | 320.0 | 276.0 | 12 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYH | P51812 | 59 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 13.3745 | 7.7126 | None | -77.26, -179.45 | -100.74, 0.21 | -62.05, -41.28 | 291.33, 112.54 | -80.3, -18.96 | out-out | out | 12.403 | Saltbr-out | 7.8685 | HRD-out | -114.7, 107.73 | -80.32, -3.28 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.5612 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooi | APE10-dihe-na | -169.14, 166.07 | APE9-dihe-na | 97.31, 158.5 | APE8-dihe-in | -62.25, 138.33 | APE8-rot-out | 53.1 | APE67-dihe-in | -70.31, -30.08 | -88.76, -15.85 | APE12-dist-none | 999.0 | APE11-dist-out | 15.6879 | APE10-dist-out | 12.1686 | APE9-dist-in | 5.1187 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | H | 320.0 | 277.0 | 13 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYI | P51812 | 63 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.4851 | 7.3943 | None | -79.8, 178.19 | -107.54, 4.76 | -62.98, -39.18 | 294.19, 109.04 | -76.4, -38.16 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -110.77, 98.18 | -69.66, 134.16 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 4.9415 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -128.64, 168.96 | APE9-dihe-na | 103.76, 142.33 | APE8-dihe-in | -52.02, 130.9 | APE8-rot-out | 52.96 | APE67-dihe-in | -63.86, -32.68 | -78.41, -20.46 | APE12-dist-none | 999.0 | APE11-dist-out | 16.5462 | APE10-dist-out | 12.6058 | APE9-dist-out | 6.6092 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | I | 320.0 | 260.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYJ | P51812 | 65 | 347 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.6806 | 7.2532 | None | -82.1, 175.26 | -103.79, -3.59 | -58.74, -48.51 | 291.22, 109.94 | -83.23, -7.51 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -111.91, 105.75 | -75.45, -19.05 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.0033 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooi | APE10-dihe-na | -112.59, 166.79 | APE9-dihe-na | 114.55, 148.33 | APE8-dihe-in | -68.28, 140.99 | APE8-rot-in | 305.08 | APE67-dihe-in | -73.95, -40.89 | -90.2, -12.76 | APE12-dist-none | 999.0 | APE11-dist-out | 16.5618 | APE10-dist-out | 12.8633 | APE9-dist-in | 5.003 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | J | 320.0 | 257.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYA | P51812 | 58 | 358 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 13.2049 | 7.3468 | None | -84.69, 175.04 | -98.49, -2.97 | -56.06, -41.49 | 288.51, 111.93 | -88.04, -1.58 | out-out | out | 13.584 | Saltbr-out | 12.4908 | HRD-out | -102.98, 108.87 | -62.66, -66.03 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.2899 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooo | APE10-dihe-na | -171.34, 174.53 | APE9-dihe-na | 132.9, 150.52 | APE8-dihe-in | -54.44, 119.7 | APE8-rot-in | 325.6 | APE67-dihe-in | -67.51, -35.24 | -72.39, -24.23 | APE12-dist-none | 999.0 | APE11-dist-out | 15.3012 | APE10-dist-out | 13.362 | APE9-dist-out | 6.3968 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | A | 320.0 | 289.0 | 12 | 28 | 19 | 9 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYB | P51812 | 59 | 358 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.4755 | 7.6225 | None | -79.21, 172.69 | -104.74, 14.38 | -72.96, -37.65 | 288.72, 121.74 | -83.1, -14.53 | out-out | out | 13.02 | Saltbr-out | 10.2513 | HRD-out | -85.11, 105.26 | -64.66, -55.07 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1807 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -141.21, 158.45 | APE9-dihe-na | 119.59, 160.83 | APE8-dihe-in | -64.8, 132.56 | APE8-rot-out | 38.16 | APE67-dihe-in | -76.3, -33.52 | -81.38, -10.91 | APE12-dist-none | 999.0 | APE11-dist-out | 15.9119 | APE10-dist-out | 12.4271 | APE9-dist-out | 6.3691 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | B | 320.0 | 277.0 | 23 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYC | P51812 | 61 | 358 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 13.0072 | 7.4047 | None | -74.08, -176.12 | -117.42, 16.75 | -70.92, -31.59 | 288.86, 115.13 | -89.42, -33.94 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -99.11, 116.77 | -79.3, -60.22 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.1388 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooo | APE10-dihe-na | -154.86, 91.8 | APE9-dihe-na | -163.03, 159.53 | APE8-dihe-in | -69.77, 116.03 | APE8-rot-in | 309.84 | APE67-dihe-in | -63.05, -25.35 | -70.36, -29.8 | APE12-dist-none | 999.0 | APE11-dist-out | 15.6924 | APE10-dist-out | 13.2566 | APE9-dist-out | 6.1853 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | C | 320.0 | 272.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYD | P51812 | 63 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.6801 | 7.7179 | None | -85.23, 171.03 | -99.91, 5.18 | -66.56, -47.9 | 288.97, 119.73 | -68.87, -42.49 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -108.97, 107.04 | -79.62, 147.57 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.0043 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -160.66, -177.37 | APE9-dihe-na | 101.82, 157.81 | APE8-dihe-in | -62.84, 132.59 | APE8-rot-out | 47.92 | APE67-dihe-in | -68.43, -26.54 | -77.35, -22.1 | APE12-dist-none | 999.0 | APE11-dist-out | 16.0048 | APE10-dist-out | 13.6407 | APE9-dist-out | 7.2804 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | D | 320.0 | 260.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYE | P51812 | 64 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.8137 | 7.7319 | None | -79.79, 173.69 | -104.44, 5.05 | -67.56, -37.65 | 296.33, 117.93 | -76.73, -31.97 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -107.95, 111.24 | -79.69, -31.85 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.217 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooi | APE10-dihe-na | -171.13, 156.06 | APE9-dihe-na | 118.15, 155.77 | APE8-dihe-in | -55.33, 128.86 | APE8-rot-out | 36.52 | APE67-dihe-in | -70.55, -22.72 | -79.46, -18.88 | APE12-dist-none | 999.0 | APE11-dist-out | 16.5561 | APE10-dist-out | 12.7625 | APE9-dist-in | 5.5786 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | E | 320.0 | 261.0 | 24 | 28 | 19 | 9 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYF | P51812 | 63 | 345 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.7435 | 7.4714 | None | -95.59, -178.42 | -108.18, 9.34 | -70.41, -40.72 | 293.14, 115.72 | -77.9, -28.8 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -100.4, 115.65 | -68.34, -48.2 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.1559 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -160.1, 173.9 | APE9-dihe-na | 114.4, 160.81 | APE8-dihe-in | -56.13, 119.9 | APE8-rot-out | 41.37 | APE67-dihe-in | -71.03, -16.28 | -73.87, -18.19 | APE12-dist-none | 999.0 | APE11-dist-out | 15.3915 | APE10-dist-out | 13.539 | APE9-dist-out | 6.404 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | F | 320.0 | 255.0 | 28 | 28 | 17 | 11 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYG | P51812 | 59 | 346 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.937 | 7.2256 | None | -78.16, 176.02 | -98.19, 0.09 | -62.25, -40.75 | 291.8, 111.06 | -81.64, -19.61 | in-out | in | 7.8808 | Saltbr-out | 5.486 | HRD-out | -91.07, 110.45 | -88.21, -3.19 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1639 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooi | APE10-dihe-na | -71.01, 158.33 | APE9-dihe-na | 129.65, 145.56 | APE8-dihe-in | -72.78, 126.88 | APE8-rot-in | 303.8 | APE67-dihe-in | -65.24, -40.51 | -67.91, -29.47 | APE12-dist-none | 999.0 | APE11-dist-out | 16.1451 | APE10-dist-out | 12.0692 | APE9-dist-in | 4.6444 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | G | 320.0 | 276.0 | 12 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYH | P51812 | 59 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 13.3745 | 7.7126 | None | -77.26, -179.45 | -100.74, 0.21 | -62.05, -41.28 | 291.33, 112.54 | -80.3, -18.96 | out-out | out | 12.403 | Saltbr-out | 7.8685 | HRD-out | -114.7, 107.73 | -80.32, -3.28 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.5612 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooi | APE10-dihe-na | -169.14, 166.07 | APE9-dihe-na | 97.31, 158.5 | APE8-dihe-in | -62.25, 138.33 | APE8-rot-out | 53.1 | APE67-dihe-in | -70.31, -30.08 | -88.76, -15.85 | APE12-dist-none | 999.0 | APE11-dist-out | 15.6879 | APE10-dist-out | 12.1686 | APE9-dist-in | 5.1187 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | H | 320.0 | 277.0 | 13 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYI | P51812 | 63 | 348 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.4851 | 7.3943 | None | -79.8, 178.19 | -107.54, 4.76 | -62.98, -39.18 | 294.19, 109.04 | -76.4, -38.16 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -110.77, 98.18 | -69.66, 134.16 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 4.9415 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nooo | APE10-dihe-na | -128.64, 168.96 | APE9-dihe-na | 103.76, 142.33 | APE8-dihe-in | -52.02, 130.9 | APE8-rot-out | 52.96 | APE67-dihe-in | -63.86, -32.68 | -78.41, -20.46 | APE12-dist-none | 999.0 | APE11-dist-out | 16.5462 | APE10-dist-out | 12.6058 | APE9-dist-out | 6.6092 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | I | 320.0 | 260.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | 8XFYJ | P51812 | 65 | 347 | 740.0 | A1LU8:401 | Type1 | Inactive | DFGout | 12.6806 | 7.2532 | None | -82.1, 175.26 | -103.79, -3.59 | -58.74, -48.51 | 291.22, 109.94 | -83.23, -7.51 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-out | -111.91, 105.75 | -75.45, -19.05 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 5.0033 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_nooi | APE10-dihe-na | -112.59, 166.79 | APE9-dihe-na | 114.55, 148.33 | APE8-dihe-in | -68.28, 140.99 | APE8-rot-in | 305.08 | APE67-dihe-in | -73.95, -40.89 | -90.2, -12.76 | APE12-dist-none | 999.0 | APE11-dist-out | 16.5618 | APE10-dist-out | 12.8633 | APE9-dist-in | 5.003 | None | None | None | XRAY | 3.2 | 0.233 | 0.303 | J | 320.0 | 257.0 | 26 | 28 | 18 | 10 | [[68, 327], [422, 679]] | 2.0 | 8xfy | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 2.5e-97 | 331.0 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|