PDB: 8V5I — STE M4K4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8V5IA
DFGout None 1 50.0% 8V5IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K4 M4K4_HUMAN 8V5IA O95819 14 309 1239.0 A1AAA:401 Type1 Inactive DFGin 6.6958 14.4044 BLAminus -123.5, 178.65 60.96, 93.48 -105.83, 16.81 281.58, 81.45 -85.41, 53.24 in-in in 8.8441 Saltbr-in 2.6928 HRD-in -57.52, -48.15 76.54, -0.01 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -74.03, 127.83 APE9-dihe-na -75.65, -135.31 APE8-dihe-in -86.64, 138.26 APE8-rot-out 184.11 APE67-dihe-in -46.08, -37.04 -88.46, -25.08 APE12-dist-in 12.2665 APE11-dist-in 11.4862 APE10-dist-out 11.2705 APE9-dist-out 9.3255 None None None XRAY 2.18 0.25 0.281 A 320.0 280.0 16 28 18 10 [[25, 289]] 1.0 8v5i STE_MAP4K4_HUMAN STE 1.5e-102 348.3 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 8V5IB O95819 16 311 1239.0 No_ligand No_ligand Inactive DFGout 16.3982 4.7739 None -64.57, 130.96 -143.69, 108.6 -121.09, 48.4 292.52, 92.46 85.4, 50.21 out-out out 14.7644 Saltbr-out 12.4066 HRD-in -69.53, -50.19 82.74, -16.12 out-out-out SNCooo out-out ActLoopNT-out 6.9023 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -66.54, -33.43 APE9-dihe-na 91.78, -165.44 APE8-dihe-in -88.83, 131.09 APE8-rot-out 196.95 APE67-dihe-in -58.07, -26.81 -94.4, -14.8 APE12-dist-out 18.5475 APE11-dist-out 17.2708 APE10-dist-out 18.5983 APE9-dist-out 9.9307 None None None XRAY 2.18 0.25 0.281 B 320.0 288.0 8 28 28 0 [[25, 289]] 1.0 8v5i STE_MAP4K4_HUMAN STE 1.5e-102 348.3 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4

PDB: 8V5I — STE M4K4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8V5IA
DFGout None 1 50.0% 8V5IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K4 M4K4_HUMAN 8V5IA O95819 14 309 1239.0 A1AAA:401 Type1 Inactive DFGin 6.6958 14.4044 BLAminus -123.5, 178.65 60.96, 93.48 -105.83, 16.81 281.58, 81.45 -85.41, 53.24 in-in in 8.8441 Saltbr-in 2.6928 HRD-in -57.52, -48.15 76.54, -0.01 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -74.03, 127.83 APE9-dihe-na -75.65, -135.31 APE8-dihe-in -86.64, 138.26 APE8-rot-out 184.11 APE67-dihe-in -46.08, -37.04 -88.46, -25.08 APE12-dist-in 12.2665 APE11-dist-in 11.4862 APE10-dist-out 11.2705 APE9-dist-out 9.3255 None None None XRAY 2.18 0.25 0.281 A 320.0 280.0 16 28 18 10 [[25, 289]] 1.0 8v5i Homo sapiens STE_MAP4K4_HUMAN STE 1.5e-102 348.3 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 8V5IB O95819 16 311 1239.0 No_ligand No_ligand Inactive DFGout 16.3982 4.7739 None -64.57, 130.96 -143.69, 108.6 -121.09, 48.4 292.52, 92.46 85.4, 50.21 out-out out 14.7644 Saltbr-out 12.4066 HRD-in -69.53, -50.19 82.74, -16.12 out-out-out SNCooo out-out ActLoopNT-out 6.9023 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -66.54, -33.43 APE9-dihe-na 91.78, -165.44 APE8-dihe-in -88.83, 131.09 APE8-rot-out 196.95 APE67-dihe-in -58.07, -26.81 -94.4, -14.8 APE12-dist-out 18.5475 APE11-dist-out 17.2708 APE10-dist-out 18.5983 APE9-dist-out 9.9307 None None None XRAY 2.18 0.25 0.281 B 320.0 288.0 8 28 28 0 [[25, 289]] 1.0 8v5i Homo sapiens STE_MAP4K4_HUMAN STE 1.5e-102 348.3 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4

PDB: 8V5I — STE M4K4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name