PDB: 8S18 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8S18A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S18A P10721 568 931 976.0 A1H4U:61001 Type2 Inactive DFGout 14.3583 9.8464 BBAminus -136.5, 172.4 -143.71, 96.71 -74.26, -23.47 290.48, 134.1 43.91, -111.27 in-in in 7.7684 Saltbr-in 2.8325 HRD-in -78.51, -51.56 81.82, -15.01 in-out-in SNCioi out-in ActLoopNT-out 16.2359 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -125.06, 109.89 APE9-dihe-in -125.76, 152.89 APE8-dihe-in -81.62, 69.52 APE8-rot-na 33.63 APE67-dihe-in -66.18, -17.82 -59.01, -39.86 APE12-dist-na 16.4919 APE11-dist-na 13.1016 APE10-dist-na 11.2511 APE9-dist-in 7.7736 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.1 0.194 0.218 A 327.0 286.0 0 30 30 0 [[589, 926]] 1.0 8s18 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S18B P10721 578 931 976.0 A1H4U:61001 Type2 Inactive DFGout 14.1082 9.4757 BBAminus -139.33, 158.91 -137.25, 115.01 -87.55, -17.15 295.29, 118.72 51.85, -119.38 in-in in 7.955 Saltbr-in 2.7671 HRD-in -75.32, -56.82 85.0, -9.46 in-out-in SNCioi out-in ActLoopNT-out 15.856 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.84, 113.28 APE9-dihe-in -126.85, 149.08 APE8-dihe-in -82.57, 70.64 APE8-rot-na 34.25 APE67-dihe-in -68.54, -17.43 -60.68, -37.6 APE12-dist-na 16.6629 APE11-dist-na 13.3739 APE10-dist-na 11.5603 APE9-dist-in 7.7784 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.1 0.194 0.218 B 327.0 276.0 0 30 30 0 [[589, 926]] 1.0 8s18 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S18 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8S18A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S18A P10721 568 931 976.0 A1H4U:61001 Type2 Inactive DFGout 14.3583 9.8464 BBAminus -136.5, 172.4 -143.71, 96.71 -74.26, -23.47 290.48, 134.1 43.91, -111.27 in-in in 7.7684 Saltbr-in 2.8325 HRD-in -78.51, -51.56 81.82, -15.01 in-out-in SNCioi out-in ActLoopNT-out 16.2359 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -125.06, 109.89 APE9-dihe-in -125.76, 152.89 APE8-dihe-in -81.62, 69.52 APE8-rot-na 33.63 APE67-dihe-in -66.18, -17.82 -59.01, -39.86 APE12-dist-na 16.4919 APE11-dist-na 13.1016 APE10-dist-na 11.2511 APE9-dist-in 7.7736 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.1 0.194 0.218 A 327.0 286.0 0 30 30 0 [[589, 926]] 1.0 8s18 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S18B P10721 578 931 976.0 A1H4U:61001 Type2 Inactive DFGout 14.1082 9.4757 BBAminus -139.33, 158.91 -137.25, 115.01 -87.55, -17.15 295.29, 118.72 51.85, -119.38 in-in in 7.955 Saltbr-in 2.7671 HRD-in -75.32, -56.82 85.0, -9.46 in-out-in SNCioi out-in ActLoopNT-out 15.856 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.84, 113.28 APE9-dihe-in -126.85, 149.08 APE8-dihe-in -82.57, 70.64 APE8-rot-na 34.25 APE67-dihe-in -68.54, -17.43 -60.68, -37.6 APE12-dist-na 16.6629 APE11-dist-na 13.3739 APE10-dist-na 11.5603 APE9-dist-in 7.7784 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.1 0.194 0.218 B 327.0 276.0 0 30 30 0 [[589, 926]] 1.0 8s18 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S18 — TYR KIT_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name