8RU8

CDK2 (Cyclin-dependent kinase 2)
Group: CMGC
Uniprot: CDK2_HUMAN
Organism: Homo sapiens
Domain boundary: 4 - 286
Resolu: 1.51

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-out none-out I74 Type1 1 - 298 14
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         2         12         22         32 
gplgspefME NFQKVEKLGE GQYGVVYKAR NKLTGEVVAL 
        42         52         62         72 
KKIRldtete gvpSTAIREI SLLKELNHPN IIKLLDVIHT 
        82         92        102        112 
ENKLYLVFEF LHQDLEVFMK ASALTGIPLP LIKSYLFQLL 
       122        132        142        152 
QGLAFCHSHR VLHRDLKPNN LLINTEGAIK LADFglaraf 
       162        172        182        192 
gvpvrtytHE VVTLWYRAPE ILLGCKYYST AVDIWSLGCI 
       202        212        222        232 
FAEMVTRRAL FPGDSEIDQL FRIFRTLGTP DEVVWPGVTS 
       242        252        262        272 
MPDYKPSFPK WARQDFSKVV PPLDEDGRSL LSQMLHYDPN 
       282        292 
KRISAKAALA HPFFQDVTKP VPHLRL
Lower-case residues are disordered in structure.
Mutations: I10L,T14Q,V64I,K88E,K89V,D92K,Q131N
Phosphorylation: None