PDB: 8PM3 — STE MP2K6_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 4 100.0% 8PM3B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K6 MP2K6_HUMAN 8PM3A P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.1398 10.9916 None -68.3, 148.34 -70.26, -27.95 -68.28, 111.48 188.26, 59.11 78.14, 13.99 out-na out 10.4402 Saltbr-na 6.2009 HRD-in -65.03, -48.31 73.37, 6.37 na-out-out SNCaoo out-out ActLoopNT-out 4.3115 ActLoopCT-out nonTYR APEdihe_aanao APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 106.98 APE8-rot-na 300.68 APE67-dihe-out -80.2, 110.27 -83.05, 148.16 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 A 290.0 272.0 15 27 17 10 [[53, 314]] 1.0 8pm3 STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 8PM3B P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.1566 11.0488 None -64.72, 147.85 -67.53, -30.45 -67.44, 111.27 186.22, 62.58 78.46, 12.48 out-na out 10.3747 Saltbr-na 6.2311 HRD-in -64.24, -48.73 73.1, 5.7 na-out-out SNCaoo out-out ActLoopNT-out 4.4397 ActLoopCT-out nonTYR APEdihe_aanao APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 128.21 APE8-rot-na 291.95 APE67-dihe-out -78.95, 106.16 -95.43, 146.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 B 290.0 273.0 14 27 17 10 [[53, 314]] 1.0 8pm3 STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 8PM3C P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.2754 11.1566 None -62.2, 146.28 -67.91, -27.86 -66.6, 110.71 183.17, 60.91 87.44, 10.06 out-na out 10.4122 Saltbr-na 6.331 HRD-in -66.26, -50.08 72.66, 3.15 na-out-out SNCaoo out-out ActLoopNT-out 4.0833 ActLoopCT-out nonTYR APEdihe_aanao APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 120.53 APE8-rot-na 271.83 APE67-dihe-out -80.13, 108.4 -78.51, 153.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 C 290.0 273.0 14 27 16 11 [[53, 314]] 1.0 8pm3 STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 8PM3D P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.2679 11.1656 None -66.56, 150.07 -72.87, -25.62 -66.14, 111.24 184.83, 57.72 85.28, 12.19 out-na out 10.4505 Saltbr-na 6.2874 HRD-in -68.52, -48.22 72.4, 4.18 na-out-none SNCaon out-none ActLoopNT-out 4.0868 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -79.51, 109.87 999.0, 135.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 D 290.0 272.0 15 27 16 11 [[53, 314]] 1.0 8pm3 STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: 8PM3 — STE MP2K6_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 4 100.0% 8PM3B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K6 MP2K6_HUMAN 8PM3A P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.1398 10.9916 None -68.3, 148.34 -70.26, -27.95 -68.28, 111.48 188.26, 59.11 78.14, 13.99 out-na out 10.4402 Saltbr-na 6.2009 HRD-in -65.03, -48.31 73.37, 6.37 na-out-out SNCaoo out-out ActLoopNT-out 4.3115 ActLoopCT-out nonTYR APEdihe_aanao APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 106.98 APE8-rot-na 300.68 APE67-dihe-out -80.2, 110.27 -83.05, 148.16 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 A 290.0 272.0 15 27 17 10 [[53, 314]] 1.0 8pm3 Homo sapiens STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 8PM3B P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.1566 11.0488 None -64.72, 147.85 -67.53, -30.45 -67.44, 111.27 186.22, 62.58 78.46, 12.48 out-na out 10.3747 Saltbr-na 6.2311 HRD-in -64.24, -48.73 73.1, 5.7 na-out-out SNCaoo out-out ActLoopNT-out 4.4397 ActLoopCT-out nonTYR APEdihe_aanao APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 128.21 APE8-rot-na 291.95 APE67-dihe-out -78.95, 106.16 -95.43, 146.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 B 290.0 273.0 14 27 17 10 [[53, 314]] 1.0 8pm3 Homo sapiens STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 8PM3C P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.2754 11.1566 None -62.2, 146.28 -67.91, -27.86 -66.6, 110.71 183.17, 60.91 87.44, 10.06 out-na out 10.4122 Saltbr-na 6.331 HRD-in -66.26, -50.08 72.66, 3.15 na-out-out SNCaoo out-out ActLoopNT-out 4.0833 ActLoopCT-out nonTYR APEdihe_aanao APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 120.53 APE8-rot-na 271.83 APE67-dihe-out -80.13, 108.4 -78.51, 153.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 C 290.0 273.0 14 27 16 11 [[53, 314]] 1.0 8pm3 Homo sapiens STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 8PM3D P52564 47 333 334.0 ZLE:401 Type1 Inactive DFGout 14.2679 11.1656 None -66.56, 150.07 -72.87, -25.62 -66.14, 111.24 184.83, 57.72 85.28, 12.19 out-na out 10.4505 Saltbr-na 6.2874 HRD-in -68.52, -48.22 72.4, 4.18 na-out-none SNCaon out-none ActLoopNT-out 4.0868 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -79.51, 109.87 999.0, 135.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None XRAY 2.0 0.198 0.236 D 290.0 272.0 15 27 16 11 [[53, 314]] 1.0 8pm3 Homo sapiens STE_MAP2K6_HUMAN STE 3.8e-85 291.3 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: 8PM3 — STE MP2K6_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name