PDB: 8EME — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8EMEB
DFGin None 1 50.0% 8EMEA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8EMEB 3.32 Inactive DFGin‑BLAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan ZNL Type1 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8EMEA 3.32 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnan APEdist_aaan No_ligand No_ligand 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor

PDB: 8EME — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8EMEB
DFGin None 1 50.0% 8EMEA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8EMEB 3.32 Inactive DFGin‑BLAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan ZNL Type1 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8EMEA 3.32 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnan APEdist_aaan No_ligand No_ligand 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 8EME — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism