| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NEK | NEK7 | NEK7_HUMAN | 8EJ4K | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7265 | 12.7016 | None | -76.42, 178.47 | -68.48, 131.61 | -71.46, 136.2 | 73.57, 100.38 | -72.87, 999.0 | out-none | out | 15.6456 | Saltbr-none | 999.0 | HRD-out | -85.33, 115.72 | -60.76, -44.72 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.68 | APE8-rot-in | 320.17 | APE67-dihe-out | -62.46, -41.14 | -76.28, 170.26 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | K | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4L | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7281 | 12.7014 | None | -76.4, 178.58 | -68.63, 131.64 | -71.57, 136.19 | 73.61, 100.3 | -72.85, 999.0 | out-none | out | 15.645 | Saltbr-none | 999.0 | HRD-out | -85.34, 115.69 | -60.77, -44.78 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.69 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.33, -41.29 | -76.38, 170.31 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | L | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4M | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7275 | 12.7029 | None | -76.4, 178.51 | -68.6, 131.68 | -71.51, 136.18 | 73.59, 100.26 | -72.74, 999.0 | out-none | out | 15.6446 | Saltbr-none | 999.0 | HRD-out | -85.42, 115.71 | -60.74, -44.77 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.73 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.39, -41.25 | -76.39, 170.39 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | M | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4N | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7275 | 12.7015 | None | -76.43, 178.48 | -68.52, 131.6 | -71.44, 136.14 | 73.59, 100.37 | -72.79, 999.0 | out-none | out | 15.6461 | Saltbr-none | 999.0 | HRD-out | -85.34, 115.77 | -60.86, -44.78 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.75 | APE8-rot-in | 320.35 | APE67-dihe-out | -62.31, -41.37 | -76.45, 170.36 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | N | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4O | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7269 | 12.7018 | None | -76.34, 178.47 | -68.49, 131.55 | -71.34, 136.17 | 73.67, 100.39 | -72.81, 999.0 | out-none | out | 15.6437 | Saltbr-none | 999.0 | HRD-out | -85.31, 115.68 | -60.76, -44.81 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.77 | APE8-rot-in | 320.21 | APE67-dihe-out | -62.36, -41.36 | -76.32, 170.28 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | O | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4P | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7286 | 12.7018 | None | -76.31, 178.45 | -68.55, 131.56 | -71.36, 136.2 | 73.73, 100.23 | -72.8, 999.0 | out-none | out | 15.6453 | Saltbr-none | 999.0 | HRD-out | -85.31, 115.58 | -60.59, -44.8 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.71 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.34, -41.31 | -76.37, 170.28 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | P | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4Q | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7278 | 12.7013 | None | -76.49, 178.43 | -68.49, 131.55 | -71.33, 136.21 | 73.64, 100.4 | -72.85, 999.0 | out-none | out | 15.6442 | Saltbr-none | 999.0 | HRD-out | -85.44, 115.71 | -60.71, -44.81 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.79 | APE8-rot-in | 320.09 | APE67-dihe-out | -62.41, -41.17 | -76.39, 170.29 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | Q | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4R | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7276 | 12.7013 | None | -76.4, 178.44 | -68.5, 131.69 | -71.51, 136.22 | 73.62, 100.38 | -72.88, 999.0 | out-none | out | 15.6433 | Saltbr-none | 999.0 | HRD-out | -85.44, 115.7 | -60.7, -44.8 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.78 | APE8-rot-in | 320.16 | APE67-dihe-out | -62.38, -41.22 | -76.37, 170.27 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | R | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4S | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7288 | 12.7035 | None | -76.31, 178.32 | -68.42, 131.55 | -71.49, 136.23 | 73.63, 100.27 | -72.77, 999.0 | out-none | out | 15.6452 | Saltbr-none | 999.0 | HRD-out | -85.28, 115.69 | -60.57, -45.0 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.74 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.31, -41.25 | -76.38, 170.27 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | S | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4T | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7275 | 12.7017 | None | -76.48, 178.46 | -68.52, 131.53 | -71.34, 136.16 | 73.66, 100.37 | -72.83, 999.0 | out-none | out | 15.6448 | Saltbr-none | 999.0 | HRD-out | -85.37, 115.71 | -60.75, -44.77 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.75 | APE8-rot-in | 320.16 | APE67-dihe-out | -62.36, -41.21 | -76.33, 170.23 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | T | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NEK | NEK7 | NEK7_HUMAN | 8EJ4K | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7265 | 12.7016 | None | -76.42, 178.47 | -68.48, 131.61 | -71.46, 136.2 | 73.57, 100.38 | -72.87, 999.0 | out-none | out | 15.6456 | Saltbr-none | 999.0 | HRD-out | -85.33, 115.72 | -60.76, -44.72 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.68 | APE8-rot-in | 320.17 | APE67-dihe-out | -62.46, -41.14 | -76.28, 170.26 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | K | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4L | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7281 | 12.7014 | None | -76.4, 178.58 | -68.63, 131.64 | -71.57, 136.19 | 73.61, 100.3 | -72.85, 999.0 | out-none | out | 15.645 | Saltbr-none | 999.0 | HRD-out | -85.34, 115.69 | -60.77, -44.78 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.69 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.33, -41.29 | -76.38, 170.31 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | L | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4M | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7275 | 12.7029 | None | -76.4, 178.51 | -68.6, 131.68 | -71.51, 136.18 | 73.59, 100.26 | -72.74, 999.0 | out-none | out | 15.6446 | Saltbr-none | 999.0 | HRD-out | -85.42, 115.71 | -60.74, -44.77 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.73 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.39, -41.25 | -76.39, 170.39 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | M | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4N | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7275 | 12.7015 | None | -76.43, 178.48 | -68.52, 131.6 | -71.44, 136.14 | 73.59, 100.37 | -72.79, 999.0 | out-none | out | 15.6461 | Saltbr-none | 999.0 | HRD-out | -85.34, 115.77 | -60.86, -44.78 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.75 | APE8-rot-in | 320.35 | APE67-dihe-out | -62.31, -41.37 | -76.45, 170.36 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | N | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4O | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7269 | 12.7018 | None | -76.34, 178.47 | -68.49, 131.55 | -71.34, 136.17 | 73.67, 100.39 | -72.81, 999.0 | out-none | out | 15.6437 | Saltbr-none | 999.0 | HRD-out | -85.31, 115.68 | -60.76, -44.81 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.77 | APE8-rot-in | 320.21 | APE67-dihe-out | -62.36, -41.36 | -76.32, 170.28 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | O | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4P | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7286 | 12.7018 | None | -76.31, 178.45 | -68.55, 131.56 | -71.36, 136.2 | 73.73, 100.23 | -72.8, 999.0 | out-none | out | 15.6453 | Saltbr-none | 999.0 | HRD-out | -85.31, 115.58 | -60.59, -44.8 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.71 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.34, -41.31 | -76.37, 170.28 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | P | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4Q | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7278 | 12.7013 | None | -76.49, 178.43 | -68.49, 131.55 | -71.33, 136.21 | 73.64, 100.4 | -72.85, 999.0 | out-none | out | 15.6442 | Saltbr-none | 999.0 | HRD-out | -85.44, 115.71 | -60.71, -44.81 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.79 | APE8-rot-in | 320.09 | APE67-dihe-out | -62.41, -41.17 | -76.39, 170.29 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | Q | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4R | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7276 | 12.7013 | None | -76.4, 178.44 | -68.5, 131.69 | -71.51, 136.22 | 73.62, 100.38 | -72.88, 999.0 | out-none | out | 15.6433 | Saltbr-none | 999.0 | HRD-out | -85.44, 115.7 | -60.7, -44.8 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.78 | APE8-rot-in | 320.16 | APE67-dihe-out | -62.38, -41.22 | -76.37, 170.27 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | R | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4S | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7288 | 12.7035 | None | -76.31, 178.32 | -68.42, 131.55 | -71.49, 136.23 | 73.63, 100.27 | -72.77, 999.0 | out-none | out | 15.6452 | Saltbr-none | 999.0 | HRD-out | -85.28, 115.69 | -60.57, -45.0 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.74 | APE8-rot-in | 320.25 | APE67-dihe-out | -62.31, -41.25 | -76.38, 170.27 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | S | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| NEK | NEK7 | NEK7_HUMAN | 8EJ4T | Q8TDX7 | 20 | 297 | 302.0 | No_ligand | No_ligand | Inactive | DFGin | 8.7275 | 12.7017 | None | -76.48, 178.46 | -68.52, 131.53 | -71.34, 136.16 | 73.66, 100.37 | -72.83, 999.0 | out-none | out | 15.6448 | Saltbr-none | 999.0 | HRD-out | -85.37, 115.71 | -60.75, -44.77 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aanio | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 134.75 | APE8-rot-in | 320.16 | APE67-dihe-out | -62.36, -41.21 | -76.33, 170.23 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | EM | 3.4 | 999.0 | 999.0 | T | 278.0 | 261.0 | 17 | 28 | 11 | 17 | [[34, 294]] | 1.0 | 8ej4 | Homo sapiens | NEK_NEK7_HUMAN | NEK | 3.1e-110 | 373.6 | 1.0 | 255.0 | 255.0 | 178 | 179 | 180 | 182 | 184 | 63 | 82 | 86 | 158 | 160 | 159 | 161.0 | 218 | 206 | 201 | 200 | 199 | 198 | 197 | 196 | 195 | 112 | Serine/threonine-protein kinase Nek7 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|