PDB: 8DGT — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8DGTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 8DGTB Q02750 43 385 393.0 AGS:60402,LCJ:60403 ATPlike,Type3 Inactive DFGin 5.9682 13.5357 BLBplus -152.99, 179.37 55.42, 45.61 -100.12, 157.06 44.99, 96.32 -80.94, 77.56 out-out out 15.5691 Saltbr-out 15.7331 HRD-in -64.15, -51.45 68.84, -11.98 out-out-out SNCooo out-out ActLoopNT-out 8.9452 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -67.75, 131.31 APE9-dihe-na -82.42, -172.83 APE8-dihe-out -101.84, -12.18 APE8-rot-out 77.74 APE67-dihe-out -124.11, 144.61 -162.74, 152.77 APE12-dist-out 16.6735 APE11-dist-out 21.6272 APE10-dist-out 23.2855 APE9-dist-out 13.7054 S218A,S222A None None EM 3.9 999.0 999.0 B 414.0 311.0 32 26 26 0 [[68, 361]] 1.0 8dgt STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 8DGTA P15056 151 738 766.0 AGS:60801 ATPlike Inactive DFGin 5.641 13.6752 BLBplus -132.23, 178.7 56.78, 46.46 -100.79, 153.62 51.93, 96.21 64.7, -132.47 out-out out 13.9231 Saltbr-out 12.693 HRD-in -71.52, -43.55 65.96, -9.54 out-out-out SNCooo out-out ActLoopNT-out 8.9984 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -155.42, 128.83 APE9-dihe-na 147.85, 157.58 APE8-dihe-in -55.44, 116.98 APE8-rot-out 39.4 APE67-dihe-in -65.02, -24.91 -67.41, -12.47 APE12-dist-out 14.3676 APE11-dist-out 14.5426 APE10-dist-out 11.9345 APE9-dist-out 6.4575 None SEP365,SEP729 SEP365,SEP729 EM 3.9 999.0 999.0 A 805.0 431.0 0 30 30 0 [[457, 716]] 1.0 8dgt TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 8DGT — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8DGTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 8DGTB Q02750 43 385 393.0 AGS:60402,LCJ:60403 ATPlike,Type3 Inactive DFGin 5.9682 13.5357 BLBplus -152.99, 179.37 55.42, 45.61 -100.12, 157.06 44.99, 96.32 -80.94, 77.56 out-out out 15.5691 Saltbr-out 15.7331 HRD-in -64.15, -51.45 68.84, -11.98 out-out-out SNCooo out-out ActLoopNT-out 8.9452 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -67.75, 131.31 APE9-dihe-na -82.42, -172.83 APE8-dihe-out -101.84, -12.18 APE8-rot-out 77.74 APE67-dihe-out -124.11, 144.61 -162.74, 152.77 APE12-dist-out 16.6735 APE11-dist-out 21.6272 APE10-dist-out 23.2855 APE9-dist-out 13.7054 S218A,S222A None None EM 3.9 999.0 999.0 B 414.0 311.0 32 26 26 0 [[68, 361]] 1.0 8dgt Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 8DGTA P15056 151 738 766.0 AGS:60801 ATPlike Inactive DFGin 5.641 13.6752 BLBplus -132.23, 178.7 56.78, 46.46 -100.79, 153.62 51.93, 96.21 64.7, -132.47 out-out out 13.9231 Saltbr-out 12.693 HRD-in -71.52, -43.55 65.96, -9.54 out-out-out SNCooo out-out ActLoopNT-out 8.9984 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -155.42, 128.83 APE9-dihe-na 147.85, 157.58 APE8-dihe-in -55.44, 116.98 APE8-rot-out 39.4 APE67-dihe-in -65.02, -24.91 -67.41, -12.47 APE12-dist-out 14.3676 APE11-dist-out 14.5426 APE10-dist-out 11.9345 APE9-dist-out 6.4575 None SEP365,SEP729 SEP365,SEP729 EM 3.9 999.0 999.0 A 805.0 431.0 0 30 30 0 [[457, 716]] 1.0 8dgt Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 8DGT — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name