PDB: 8DGS — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8DGSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 8DGSB Q02750 38 383 393.0 AGS:60801,LCJ:60803 ATPlike,Type1 Inactive DFGin 6.249 12.9971 BLBplus -155.73, -179.02 61.68, 27.26 -72.39, 155.67 44.5, 85.53 -87.2, 64.42 out-out out 16.2947 Saltbr-out 16.06 HRD-in -62.57, -46.0 64.99, -4.53 out-out-out SNCooo out-out ActLoopNT-out 8.7094 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -122.25, 153.26 APE9-dihe-na -110.07, 177.24 APE8-dihe-out -99.46, -47.43 APE8-rot-out 69.24 APE67-dihe-out -133.48, 170.62 -132.77, 150.72 APE12-dist-out 17.1114 APE11-dist-out 20.5769 APE10-dist-out 22.9193 APE9-dist-out 13.2707 S218A,S222A None None EM 4.3 999.0 999.0 B 414.0 314.0 32 26 26 0 [[68, 361]] 1.0 8dgs STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 8DGSA P15056 155 738 766.0 AGS:60801 ATPlike Inactive DFGin 6.6063 13.2375 BLBplus -138.09, -166.17 58.48, 64.88 -134.87, 173.46 48.16, 90.78 58.1, -132.32 out-out out 14.5219 Saltbr-out 12.2584 HRD-in -71.36, -47.09 71.02, -12.92 out-out-out SNCooo out-out ActLoopNT-out 9.5544 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -160.2, 161.72 APE9-dihe-na 103.44, -137.95 APE8-dihe-in -102.25, 169.61 APE8-rot-in 312.72 APE67-dihe-in -64.56, -41.44 -121.48, -15.09 APE12-dist-out 14.0817 APE11-dist-out 15.8432 APE10-dist-out 12.4597 APE9-dist-out 8.209 None SEP365,SEP729 SEP365,SEP729 EM 4.3 999.0 999.0 A 805.0 427.0 0 30 30 0 [[457, 716]] 1.0 8dgs TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 8DGS — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8DGSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 8DGSB Q02750 38 383 393.0 AGS:60801,LCJ:60803 ATPlike,Type1 Inactive DFGin 6.249 12.9971 BLBplus -155.73, -179.02 61.68, 27.26 -72.39, 155.67 44.5, 85.53 -87.2, 64.42 out-out out 16.2947 Saltbr-out 16.06 HRD-in -62.57, -46.0 64.99, -4.53 out-out-out SNCooo out-out ActLoopNT-out 8.7094 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -122.25, 153.26 APE9-dihe-na -110.07, 177.24 APE8-dihe-out -99.46, -47.43 APE8-rot-out 69.24 APE67-dihe-out -133.48, 170.62 -132.77, 150.72 APE12-dist-out 17.1114 APE11-dist-out 20.5769 APE10-dist-out 22.9193 APE9-dist-out 13.2707 S218A,S222A None None EM 4.3 999.0 999.0 B 414.0 314.0 32 26 26 0 [[68, 361]] 1.0 8dgs Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 8DGSA P15056 155 738 766.0 AGS:60801 ATPlike Inactive DFGin 6.6063 13.2375 BLBplus -138.09, -166.17 58.48, 64.88 -134.87, 173.46 48.16, 90.78 58.1, -132.32 out-out out 14.5219 Saltbr-out 12.2584 HRD-in -71.36, -47.09 71.02, -12.92 out-out-out SNCooo out-out ActLoopNT-out 9.5544 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -160.2, 161.72 APE9-dihe-na 103.44, -137.95 APE8-dihe-in -102.25, 169.61 APE8-rot-in 312.72 APE67-dihe-in -64.56, -41.44 -121.48, -15.09 APE12-dist-out 14.0817 APE11-dist-out 15.8432 APE10-dist-out 12.4597 APE9-dist-out 8.209 None SEP365,SEP729 SEP365,SEP729 EM 4.3 999.0 999.0 A 805.0 427.0 0 30 30 0 [[457, 716]] 1.0 8dgs Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 8DGS — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name