PDB: 8A8M — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8A8MB
None None 1 50.0% 8A8MA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK14 MK14_HUMAN 8A8MA 4.0 Inactive None‑None in-out out-out nonTYR APEdihe_aaioo APEdist_oooo AP2 Type1 5 - 353 0 None T180V Mitogen-activated protein kinase 14
STE MAP2K6 MP2K6_HUMAN 8A8MB 4.0 None DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn AP2 Type1 38 - 334 0 None S207D,T211D Dual specificity mitogen-activated protein kinase kinase 6

PDB: 8A8M — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8A8MB
None None 1 50.0% 8A8MA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_HUMAN 8A8MA 4.0 Inactive None‑None in-out out-out nonTYR APEdihe_aaioo APEdist_oooo AP2 Type1 5 - 353 0 None T180V Mitogen-activated protein kinase 14 Homo sapiens
STE MAP2K6 MP2K6_HUMAN 8A8MB 4.0 None DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn AP2 Type1 38 - 334 0 None S207D,T211D Dual specificity mitogen-activated protein kinase kinase 6 Homo sapiens

PDB: 8A8M — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism