PDB: 8A8M — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8A8MB
None None 1 50.0% 8A8MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 8A8MA Q16539 5 353 360.0 AP2:60900 Type1 Inactive None 11.0583 18.3662 None -133.1, -179.58 58.18, 65.77 -88.58, 125.42 201.03, 134.23 104.29, 124.16 in-out in 8.1966 Saltbr-out 9.5148 HRD-in -64.82, -44.91 64.86, -2.06 out-out-out SNCooo out-out ActLoopNT-out 6.9629 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -131.1, 94.25 APE9-dihe-na -165.78, 126.4 APE8-dihe-in -95.27, 137.04 APE8-rot-out 60.89 APE67-dihe-out 70.19, 13.63 -115.98, -56.13 APE12-dist-out 23.1068 APE11-dist-out 21.7967 APE10-dist-out 23.4916 APE9-dist-out 14.1872 T180V None None EM 4.0 999.0 999.0 A 381.0 349.0 0 25 25 0 [[24, 308]] 1.0 8a8m CMGC_MAPK14_HUMAN CMGC 4e-84 288.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
STE MAP2K6 MP2K6_HUMAN 8A8MB P52564 38 334 334.0 AP2:60401 Type1 None DFGin 5.4863 11.6397 BLAminus -146.69, -172.97 54.53, 63.91 -81.56, 13.5 331.49, 114.43 -66.25, -37.97 in-na in 8.6147 Saltbr-na 5.512 HRD-in -64.64, -38.02 67.87, -2.84 na-in-none SNCain in-none ActLoopNT-in 3.1849 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -48.81 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None EM 4.0 999.0 999.0 B 374.0 284.0 13 27 14 13 [[53, 314]] 1.0 8a8m STE_MAP2K6_HUMAN STE 8.9e-85 290.1 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: 8A8M — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8A8MB
None None 1 50.0% 8A8MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_HUMAN 8A8MA Q16539 5 353 360.0 AP2:60900 Type1 Inactive None 11.0583 18.3662 None -133.1, -179.58 58.18, 65.77 -88.58, 125.42 201.03, 134.23 104.29, 124.16 in-out in 8.1966 Saltbr-out 9.5148 HRD-in -64.82, -44.91 64.86, -2.06 out-out-out SNCooo out-out ActLoopNT-out 6.9629 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -131.1, 94.25 APE9-dihe-na -165.78, 126.4 APE8-dihe-in -95.27, 137.04 APE8-rot-out 60.89 APE67-dihe-out 70.19, 13.63 -115.98, -56.13 APE12-dist-out 23.1068 APE11-dist-out 21.7967 APE10-dist-out 23.4916 APE9-dist-out 14.1872 T180V None None EM 4.0 999.0 999.0 A 381.0 349.0 0 25 25 0 [[24, 308]] 1.0 8a8m Homo sapiens CMGC_MAPK14_HUMAN CMGC 4e-84 288.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
STE MAP2K6 MP2K6_HUMAN 8A8MB P52564 38 334 334.0 AP2:60401 Type1 None DFGin 5.4863 11.6397 BLAminus -146.69, -172.97 54.53, 63.91 -81.56, 13.5 331.49, 114.43 -66.25, -37.97 in-na in 8.6147 Saltbr-na 5.512 HRD-in -64.64, -38.02 67.87, -2.84 na-in-none SNCain in-none ActLoopNT-in 3.1849 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -48.81 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None None EM 4.0 999.0 999.0 B 374.0 284.0 13 27 14 13 [[53, 314]] 1.0 8a8m Homo sapiens STE_MAP2K6_HUMAN STE 8.9e-85 290.1 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: 8A8M — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name