PDB: 7S25 — AGC ROCK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 3 75.0% 7S25B
None None 1 25.0% 7S25D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC ROCK1 ROCK1_HUMAN 7S25A Q13464 7 401 1354.0 86G:504 Type1 Inactive DFGout 12.3182 10.5395 None -104.78, 156.55 -123.71, 119.26 -167.75, -177.1 52.05, 88.34 -122.16, 999.0 in-in in 8.4534 Saltbr-in 2.7603 HRD-in -48.48, -35.86 65.44, -17.99 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -126.37 APE8-dihe-in -84.85, 138.74 APE8-rot-in 343.84 APE67-dihe-in -53.73, -33.25 -65.56, -53.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 6.1051 None None None XRAY 2.337 0.24 0.271 A 396.0 373.0 22 29 12 17 [[76, 338]] 1.0 7s25 AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S25B Q13464 8 402 1354.0 86G:501 Type1 Inactive DFGout 12.1606 10.1444 None -102.96, 170.2 -133.51, 102.53 -164.51, 160.19 55.37, 93.46 -104.18, 142.28 in-in in 8.6472 Saltbr-in 2.7102 HRD-in -64.3, -54.36 69.65, -10.64 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -102.96, -6.09 APE9-dihe-na 73.94, -123.45 APE8-dihe-in -79.15, 120.74 APE8-rot-in 312.82 APE67-dihe-in -46.47, -33.29 -85.89, -15.42 APE12-dist-in 11.3205 APE11-dist-in 11.3061 APE10-dist-out 9.4116 APE9-dist-out 8.4049 None None None XRAY 2.337 0.24 0.271 B 396.0 379.0 12 29 17 12 [[76, 338]] 1.0 7s25 AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S25C Q13464 13 402 1354.0 86G:501 Type1 Inactive DFGout 12.6929 10.5438 None -104.89, 170.47 -133.65, 98.69 -152.01, 158.42 54.9, 83.0 -75.12, 999.0 in-in in 8.5051 Saltbr-in 2.7988 HRD-in -63.41, -47.95 72.04, -26.33 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 89.67 APE8-rot-out 72.08 APE67-dihe-in -54.43, -34.25 -48.72, -39.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.337 0.24 0.271 C 396.0 361.0 18 29 11 18 [[76, 338]] 1.0 7s25 AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S25D Q13464 9 401 1354.0 No_ligand No_ligand Inactive None 999.0 999.0 None -105.32, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 in-in in 8.4721 Saltbr-in 2.7334 HRD-in -82.09, -47.81 61.94, 11.48 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.337 0.24 0.271 D 396.0 257.0 113 29 0 29 [[76, 338]] 1.0 7s25 AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1

PDB: 7S25 — AGC ROCK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 3 75.0% 7S25B
None None 1 25.0% 7S25D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC ROCK1 ROCK1_HUMAN 7S25A Q13464 7 401 1354.0 86G:504 Type1 Inactive DFGout 12.3182 10.5395 None -104.78, 156.55 -123.71, 119.26 -167.75, -177.1 52.05, 88.34 -122.16, 999.0 in-in in 8.4534 Saltbr-in 2.7603 HRD-in -48.48, -35.86 65.44, -17.99 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -126.37 APE8-dihe-in -84.85, 138.74 APE8-rot-in 343.84 APE67-dihe-in -53.73, -33.25 -65.56, -53.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 6.1051 None None None XRAY 2.337 0.24 0.271 A 396.0 373.0 22 29 12 17 [[76, 338]] 1.0 7s25 Homo sapiens AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S25B Q13464 8 402 1354.0 86G:501 Type1 Inactive DFGout 12.1606 10.1444 None -102.96, 170.2 -133.51, 102.53 -164.51, 160.19 55.37, 93.46 -104.18, 142.28 in-in in 8.6472 Saltbr-in 2.7102 HRD-in -64.3, -54.36 69.65, -10.64 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -102.96, -6.09 APE9-dihe-na 73.94, -123.45 APE8-dihe-in -79.15, 120.74 APE8-rot-in 312.82 APE67-dihe-in -46.47, -33.29 -85.89, -15.42 APE12-dist-in 11.3205 APE11-dist-in 11.3061 APE10-dist-out 9.4116 APE9-dist-out 8.4049 None None None XRAY 2.337 0.24 0.271 B 396.0 379.0 12 29 17 12 [[76, 338]] 1.0 7s25 Homo sapiens AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S25C Q13464 13 402 1354.0 86G:501 Type1 Inactive DFGout 12.6929 10.5438 None -104.89, 170.47 -133.65, 98.69 -152.01, 158.42 54.9, 83.0 -75.12, 999.0 in-in in 8.5051 Saltbr-in 2.7988 HRD-in -63.41, -47.95 72.04, -26.33 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 89.67 APE8-rot-out 72.08 APE67-dihe-in -54.43, -34.25 -48.72, -39.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.337 0.24 0.271 C 396.0 361.0 18 29 11 18 [[76, 338]] 1.0 7s25 Homo sapiens AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 7S25D Q13464 9 401 1354.0 No_ligand No_ligand Inactive None 999.0 999.0 None -105.32, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 in-in in 8.4721 Saltbr-in 2.7334 HRD-in -82.09, -47.81 61.94, 11.48 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.337 0.24 0.271 D 396.0 257.0 113 29 0 29 [[76, 338]] 1.0 7s25 Homo sapiens AGC_ROCK1_HUMAN AGC 3e-94 320.9 1.0 260.0 260.0 215 216 217 219 221 105 124 128 195 197 196 198.0 260 244 239 238 237 236 235 234 233 154 Rho-associated protein kinase 1

PDB: 7S25 — AGC ROCK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name