7RUN

RET (Proto-oncogene tyrosine-protein kinase receptor Ret)
Group: TYR
Uniprot: RET_HUMAN
Organism: Homo sapiens
Domain boundary: 724 - 1007
Resolu: 3.51

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 7QU Type1.5_Back 705 - 1012 0
B Active DFGin BLAminus in-in in-in 7QU Type1.5_Back 706 - 1012 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -        709        719 
msyyhhhhhh dydipttenl yfqgasVDAF KILEDPKWEF 
       729        739        749        759 
PRKNLVLGKT LGEGEFGKVV KATAFHLKGR AGYTTVAVKM 
       769        779        789        799 
LKENASPSEL RDLLSEFNVL KQVNHPHVIK LYGACSQDGP 
       809        819        829        839 
LLLIVEYAKY GSLRGFLRES RKVGPgylgs ggsrnsssld 
       849        859        869        879 
hpdeRALTMG DLISFAWQIS QGMQYLAEMK LVHRDLAARN 
       889        899        909        919 
ILVAEGRKMK ISDFGLSRDV YEEDSYVKRS QGRIPVKWMA 
       929        939        949        959 
IESLFDHIYT TQSDVWSFGV LLWEIVTLGG NPYPGIPPER 
       969        979        989        999 
LFNLLKTGHR MERPDNCSEE MYRLMLQCWK QEPDKRPVFA 
      1009 
DISKDLEKMM VKRr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X809,X905,X909,X928