PDB: 7MFD — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7MFDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7MFDB Q02750 52 383 393.0 CHU:401 Type3 Inactive DFGin 5.404 15.0019 BLBplus -158.62, 167.12 60.92, 63.61 -97.12, -175.46 63.42, 90.2 -85.78, 95.16 out-out out 16.3227 Saltbr-out 15.7256 HRD-in -63.97, -52.79 67.43, -4.72 out-out-out SNCooo out-out ActLoopNT-out 9.6757 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -74.44, -63.74 APE9-dihe-na 63.29, 177.26 APE8-dihe-out -134.0, -13.26 APE8-rot-out 186.3 APE67-dihe-out -128.3, 117.83 -113.33, 134.88 APE12-dist-out 15.8757 APE11-dist-out 14.2111 APE10-dist-out 20.3493 APE9-dist-out 12.7512 None None None EM 3.66 999.0 999.0 B 393.0 293.0 39 26 26 0 [[68, 361]] 1.0 7mfd STE_MAP2K1_HUMAN STE 2.4e-97 331.4 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7MFDA P15056 156 738 766.0 No_ligand No_ligand Inactive DFGin 6.1335 14.0284 BLBplus -147.17, -167.77 58.95, 63.63 -141.3, 173.3 63.34, 90.1 84.7, -138.28 out-out out 13.4444 Saltbr-out 14.9642 HRD-in -65.44, -45.07 53.09, 12.91 out-out-out SNCooo out-out ActLoopNT-out 10.1255 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iooo APE10-dihe-na -115.53, 118.71 APE9-dihe-na 124.14, -152.32 APE8-dihe-out -80.3, -174.47 APE8-rot-out 175.42 APE67-dihe-in -88.54, -38.49 -131.9, 1.65 APE12-dist-in 12.524 APE11-dist-out 15.2931 APE10-dist-out 11.9411 APE9-dist-out 9.0062 None SEP365,SEP729 SEP365,SEP729 EM 3.66 999.0 999.0 A 766.0 410.0 0 30 30 0 [[457, 716]] 1.0 7mfd TKL_BRAF_HUMAN TKL 1.3e-80 277.1 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7MFD — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7MFDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7MFDB Q02750 52 383 393.0 CHU:401 Type3 Inactive DFGin 5.404 15.0019 BLBplus -158.62, 167.12 60.92, 63.61 -97.12, -175.46 63.42, 90.2 -85.78, 95.16 out-out out 16.3227 Saltbr-out 15.7256 HRD-in -63.97, -52.79 67.43, -4.72 out-out-out SNCooo out-out ActLoopNT-out 9.6757 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -74.44, -63.74 APE9-dihe-na 63.29, 177.26 APE8-dihe-out -134.0, -13.26 APE8-rot-out 186.3 APE67-dihe-out -128.3, 117.83 -113.33, 134.88 APE12-dist-out 15.8757 APE11-dist-out 14.2111 APE10-dist-out 20.3493 APE9-dist-out 12.7512 None None None EM 3.66 999.0 999.0 B 393.0 293.0 39 26 26 0 [[68, 361]] 1.0 7mfd Homo sapiens STE_MAP2K1_HUMAN STE 2.4e-97 331.4 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7MFDA P15056 156 738 766.0 No_ligand No_ligand Inactive DFGin 6.1335 14.0284 BLBplus -147.17, -167.77 58.95, 63.63 -141.3, 173.3 63.34, 90.1 84.7, -138.28 out-out out 13.4444 Saltbr-out 14.9642 HRD-in -65.44, -45.07 53.09, 12.91 out-out-out SNCooo out-out ActLoopNT-out 10.1255 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iooo APE10-dihe-na -115.53, 118.71 APE9-dihe-na 124.14, -152.32 APE8-dihe-out -80.3, -174.47 APE8-rot-out 175.42 APE67-dihe-in -88.54, -38.49 -131.9, 1.65 APE12-dist-in 12.524 APE11-dist-out 15.2931 APE10-dist-out 11.9411 APE9-dist-out 9.0062 None SEP365,SEP729 SEP365,SEP729 EM 3.66 999.0 999.0 A 766.0 410.0 0 30 30 0 [[457, 716]] 1.0 7mfd Homo sapiens TKL_BRAF_HUMAN TKL 1.3e-80 277.1 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7MFD — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name