PDB: 7M0Z — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0ZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0ZB Q02750 42 383 393.0 ANP:401,CHU:402 ATPlike,Type3 Inactive DFGin 6.1064 14.1069 BLBplus -160.77, 175.85 59.87, 41.63 -97.41, 152.84 45.88, 80.73 -66.99, 92.55 out-out out 15.4927 Saltbr-out 15.371 HRD-in -96.91, -40.79 69.65, -8.88 out-out-out SNCooo out-out ActLoopNT-out 9.612 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -66.4, 138.99 APE9-dihe-na -84.75, -165.15 APE8-dihe-out -106.74, -38.37 APE8-rot-out 38.19 APE67-dihe-out -129.38, 138.55 -136.73, 157.33 APE12-dist-out 17.2133 APE11-dist-out 22.3822 APE10-dist-out 23.6126 APE9-dist-out 13.6034 S218A,S222A None None XRAY 3.12 0.193 0.225 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0z STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0ZA P15056 449 721 766.0 ANP:801 ATPlike Inactive DFGin 5.5912 13.5576 BLBplus -131.23, -177.35 57.24, 31.09 -88.02, 155.4 49.99, 89.35 66.37, -137.56 out-out out 14.3781 Saltbr-out 12.7969 HRD-in -63.1, -49.11 70.7, -2.29 out-out-out SNCooo out-out ActLoopNT-out 8.9341 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooo APE10-dihe-na -140.88, 158.66 APE9-dihe-na 126.45, -167.01 APE8-dihe-in -93.79, 132.25 APE8-rot-out 208.38 APE67-dihe-in -66.35, -24.31 -75.16, -20.55 APE12-dist-in 12.9869 APE11-dist-out 14.9185 APE10-dist-out 11.8215 APE9-dist-out 6.3849 None None None XRAY 3.12 0.193 0.225 A 283.0 273.0 0 30 30 0 [[457, 716]] 1.0 7m0z TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0Z — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0ZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0ZB Q02750 42 383 393.0 ANP:401,CHU:402 ATPlike,Type3 Inactive DFGin 6.1064 14.1069 BLBplus -160.77, 175.85 59.87, 41.63 -97.41, 152.84 45.88, 80.73 -66.99, 92.55 out-out out 15.4927 Saltbr-out 15.371 HRD-in -96.91, -40.79 69.65, -8.88 out-out-out SNCooo out-out ActLoopNT-out 9.612 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -66.4, 138.99 APE9-dihe-na -84.75, -165.15 APE8-dihe-out -106.74, -38.37 APE8-rot-out 38.19 APE67-dihe-out -129.38, 138.55 -136.73, 157.33 APE12-dist-out 17.2133 APE11-dist-out 22.3822 APE10-dist-out 23.6126 APE9-dist-out 13.6034 S218A,S222A None None XRAY 3.12 0.193 0.225 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0z Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0ZA P15056 449 721 766.0 ANP:801 ATPlike Inactive DFGin 5.5912 13.5576 BLBplus -131.23, -177.35 57.24, 31.09 -88.02, 155.4 49.99, 89.35 66.37, -137.56 out-out out 14.3781 Saltbr-out 12.7969 HRD-in -63.1, -49.11 70.7, -2.29 out-out-out SNCooo out-out ActLoopNT-out 8.9341 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooo APE10-dihe-na -140.88, 158.66 APE9-dihe-na 126.45, -167.01 APE8-dihe-in -93.79, 132.25 APE8-rot-out 208.38 APE67-dihe-in -66.35, -24.31 -75.16, -20.55 APE12-dist-in 12.9869 APE11-dist-out 14.9185 APE10-dist-out 11.8215 APE9-dist-out 6.3849 None None None XRAY 3.12 0.193 0.225 A 283.0 273.0 0 30 30 0 [[457, 716]] 1.0 7m0z Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0Z — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name