PDB: 7M0Y — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0YB Q02750 43 382 393.0 ANP:401,QOM:404 ATPlike,Type3 Inactive DFGin 5.9314 13.9674 BLBplus -158.94, 162.56 56.25, 36.06 -89.69, 147.0 54.27, 82.92 -67.13, 108.1 out-out out 15.4927 Saltbr-out 15.9617 HRD-in -58.74, -61.39 74.04, 6.51 out-out-out SNCooo out-out ActLoopNT-out 9.4018 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -63.76, 140.76 APE9-dihe-na -82.11, -165.89 APE8-dihe-out -109.48, -23.44 APE8-rot-out 48.75 APE67-dihe-out -133.69, 134.38 -151.5, 158.4 APE12-dist-out 17.3805 APE11-dist-out 22.4528 APE10-dist-out 23.379 APE9-dist-out 13.66 S218A,S222A None None XRAY 3.45 0.196 0.218 B 397.0 308.0 32 26 26 0 [[68, 361]] 1.0 7m0y STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0YA P15056 447 721 766.0 ANP:801 ATPlike Inactive DFGin 5.9246 13.72 BLBplus -130.12, 178.08 53.67, 39.87 -94.09, 143.26 51.07, 86.66 77.46, -140.33 out-out out 14.4541 Saltbr-out 12.4204 HRD-in -66.6, -53.86 81.89, -14.1 out-out-out SNCooo out-out ActLoopNT-out 8.9677 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -138.96, 162.77 APE9-dihe-na 110.62, -175.34 APE8-dihe-in -77.87, 138.5 APE8-rot-out 52.44 APE67-dihe-in -64.93, -32.89 -83.52, -17.07 APE12-dist-out 14.2255 APE11-dist-out 15.2702 APE10-dist-out 12.0065 APE9-dist-out 6.7809 None None None XRAY 3.45 0.196 0.218 A 283.0 275.0 0 30 30 0 [[457, 716]] 1.0 7m0y TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0Y — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0YB Q02750 43 382 393.0 ANP:401,QOM:404 ATPlike,Type3 Inactive DFGin 5.9314 13.9674 BLBplus -158.94, 162.56 56.25, 36.06 -89.69, 147.0 54.27, 82.92 -67.13, 108.1 out-out out 15.4927 Saltbr-out 15.9617 HRD-in -58.74, -61.39 74.04, 6.51 out-out-out SNCooo out-out ActLoopNT-out 9.4018 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -63.76, 140.76 APE9-dihe-na -82.11, -165.89 APE8-dihe-out -109.48, -23.44 APE8-rot-out 48.75 APE67-dihe-out -133.69, 134.38 -151.5, 158.4 APE12-dist-out 17.3805 APE11-dist-out 22.4528 APE10-dist-out 23.379 APE9-dist-out 13.66 S218A,S222A None None XRAY 3.45 0.196 0.218 B 397.0 308.0 32 26 26 0 [[68, 361]] 1.0 7m0y Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0YA P15056 447 721 766.0 ANP:801 ATPlike Inactive DFGin 5.9246 13.72 BLBplus -130.12, 178.08 53.67, 39.87 -94.09, 143.26 51.07, 86.66 77.46, -140.33 out-out out 14.4541 Saltbr-out 12.4204 HRD-in -66.6, -53.86 81.89, -14.1 out-out-out SNCooo out-out ActLoopNT-out 8.9677 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -138.96, 162.77 APE9-dihe-na 110.62, -175.34 APE8-dihe-in -77.87, 138.5 APE8-rot-out 52.44 APE67-dihe-in -64.93, -32.89 -83.52, -17.07 APE12-dist-out 14.2255 APE11-dist-out 15.2702 APE10-dist-out 12.0065 APE9-dist-out 6.7809 None None None XRAY 3.45 0.196 0.218 A 283.0 275.0 0 30 30 0 [[457, 716]] 1.0 7m0y Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0Y — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name