PDB: 7M0X — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0XA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0XB Q02750 40 383 393.0 ANP:801,4BM:803 ATPlike,Type3 Inactive DFGin 6.0399 13.7075 BLBplus -145.13, 173.52 62.48, 32.29 -85.3, 166.26 43.84, 89.91 -82.62, 63.8 out-out out 15.2193 Saltbr-out 15.1277 HRD-in -57.93, -57.46 71.94, -0.74 out-out-out SNCooo out-out ActLoopNT-out 8.3308 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -140.02, 147.44 APE9-dihe-na -87.47, -179.23 APE8-dihe-out -111.82, -15.11 APE8-rot-out 56.07 APE67-dihe-out -151.04, 140.91 -141.23, 175.81 APE12-dist-out 17.7952 APE11-dist-out 17.9191 APE10-dist-out 21.3926 APE9-dist-out 11.9857 S218A,S222A None None XRAY 2.47 0.18 0.215 B 397.0 312.0 32 26 26 0 [[68, 361]] 1.0 7m0x STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0XA P15056 447 722 766.0 ANP:801 ATPlike Inactive DFGin 5.4453 13.4953 BLBplus -123.82, 174.92 60.79, 42.33 -96.45, 161.16 49.04, 90.67 58.85, -140.33 out-out out 14.2652 Saltbr-out 13.0632 HRD-in -65.53, -50.34 78.03, -10.0 out-out-out SNCooo out-out ActLoopNT-out 9.2452 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -141.24, 149.26 APE9-dihe-na 65.43, -162.66 APE8-dihe-in -61.59, 142.77 APE8-rot-out 179.57 APE67-dihe-in -62.52, -26.23 -97.92, -3.07 APE12-dist-out 15.152 APE11-dist-out 15.9657 APE10-dist-out 12.6259 APE9-dist-out 10.0835 None None None XRAY 2.47 0.18 0.215 A 283.0 276.0 0 30 30 0 [[457, 716]] 1.0 7m0x TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0X — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0XA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0XB Q02750 40 383 393.0 ANP:801,4BM:803 ATPlike,Type3 Inactive DFGin 6.0399 13.7075 BLBplus -145.13, 173.52 62.48, 32.29 -85.3, 166.26 43.84, 89.91 -82.62, 63.8 out-out out 15.2193 Saltbr-out 15.1277 HRD-in -57.93, -57.46 71.94, -0.74 out-out-out SNCooo out-out ActLoopNT-out 8.3308 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -140.02, 147.44 APE9-dihe-na -87.47, -179.23 APE8-dihe-out -111.82, -15.11 APE8-rot-out 56.07 APE67-dihe-out -151.04, 140.91 -141.23, 175.81 APE12-dist-out 17.7952 APE11-dist-out 17.9191 APE10-dist-out 21.3926 APE9-dist-out 11.9857 S218A,S222A None None XRAY 2.47 0.18 0.215 B 397.0 312.0 32 26 26 0 [[68, 361]] 1.0 7m0x Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0XA P15056 447 722 766.0 ANP:801 ATPlike Inactive DFGin 5.4453 13.4953 BLBplus -123.82, 174.92 60.79, 42.33 -96.45, 161.16 49.04, 90.67 58.85, -140.33 out-out out 14.2652 Saltbr-out 13.0632 HRD-in -65.53, -50.34 78.03, -10.0 out-out-out SNCooo out-out ActLoopNT-out 9.2452 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -141.24, 149.26 APE9-dihe-na 65.43, -162.66 APE8-dihe-in -61.59, 142.77 APE8-rot-out 179.57 APE67-dihe-in -62.52, -26.23 -97.92, -3.07 APE12-dist-out 15.152 APE11-dist-out 15.9657 APE10-dist-out 12.6259 APE9-dist-out 10.0835 None None None XRAY 2.47 0.18 0.215 A 283.0 276.0 0 30 30 0 [[457, 716]] 1.0 7m0x Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0X — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name