PDB: 7M0W — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0WB Q02750 42 383 393.0 ANP:801,QOA:803 ATPlike,Type3 Inactive DFGin 6.1482 14.0545 BLBplus -157.1, -177.15 57.47, 39.21 -94.37, 139.97 49.64, 89.26 -60.24, 75.28 out-out out 15.239 Saltbr-out 15.1806 HRD-in -60.24, -53.72 67.58, 4.61 out-out-out SNCooo out-out ActLoopNT-out 8.8656 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -57.72, 142.94 APE9-dihe-na -85.2, -169.93 APE8-dihe-out -102.45, -22.28 APE8-rot-out 37.77 APE67-dihe-out -129.82, 144.3 -151.67, 158.88 APE12-dist-out 17.5121 APE11-dist-out 22.6571 APE10-dist-out 23.4774 APE9-dist-out 13.5899 S218A,S222A None None XRAY 3.09 0.197 0.233 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0w STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0WA P15056 448 721 766.0 ANP:801 ATPlike Inactive DFGin 5.6996 13.563 BLBplus -128.57, -174.24 58.52, 36.11 -93.32, 163.98 47.26, 91.72 57.0, -141.37 out-out out 14.2729 Saltbr-out 13.0439 HRD-in -64.47, -50.11 78.2, -6.17 out-out-out SNCooo out-out ActLoopNT-out 8.9804 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -140.16, 158.71 APE9-dihe-na 121.26, -178.69 APE8-dihe-in -87.94, 138.93 APE8-rot-out 43.99 APE67-dihe-in -65.6, -30.89 -79.08, -13.62 APE12-dist-out 14.335 APE11-dist-out 15.3422 APE10-dist-out 12.1341 APE9-dist-out 6.6508 None None None XRAY 3.09 0.197 0.233 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0w TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0W — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0WB Q02750 42 383 393.0 ANP:801,QOA:803 ATPlike,Type3 Inactive DFGin 6.1482 14.0545 BLBplus -157.1, -177.15 57.47, 39.21 -94.37, 139.97 49.64, 89.26 -60.24, 75.28 out-out out 15.239 Saltbr-out 15.1806 HRD-in -60.24, -53.72 67.58, 4.61 out-out-out SNCooo out-out ActLoopNT-out 8.8656 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -57.72, 142.94 APE9-dihe-na -85.2, -169.93 APE8-dihe-out -102.45, -22.28 APE8-rot-out 37.77 APE67-dihe-out -129.82, 144.3 -151.67, 158.88 APE12-dist-out 17.5121 APE11-dist-out 22.6571 APE10-dist-out 23.4774 APE9-dist-out 13.5899 S218A,S222A None None XRAY 3.09 0.197 0.233 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0w Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0WA P15056 448 721 766.0 ANP:801 ATPlike Inactive DFGin 5.6996 13.563 BLBplus -128.57, -174.24 58.52, 36.11 -93.32, 163.98 47.26, 91.72 57.0, -141.37 out-out out 14.2729 Saltbr-out 13.0439 HRD-in -64.47, -50.11 78.2, -6.17 out-out-out SNCooo out-out ActLoopNT-out 8.9804 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -140.16, 158.71 APE9-dihe-na 121.26, -178.69 APE8-dihe-in -87.94, 138.93 APE8-rot-out 43.99 APE67-dihe-in -65.6, -30.89 -79.08, -13.62 APE12-dist-out 14.335 APE11-dist-out 15.3422 APE10-dist-out 12.1341 APE9-dist-out 6.6508 None None None XRAY 3.09 0.197 0.233 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0w Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0W — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name