PDB: 7M0V — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0VB Q02750 42 383 393.0 ANP:801,EUI:803 ATPlike,Type3 Inactive DFGin 6.0381 13.7379 BLBplus -152.98, 176.74 51.89, 40.05 -97.58, 155.01 48.54, 94.68 -74.32, 76.65 out-out out 15.3562 Saltbr-out 15.2475 HRD-in -53.62, -41.23 79.48, -8.01 out-out-out SNCooo out-out ActLoopNT-out 8.4508 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -59.78, 136.18 APE9-dihe-na -90.07, -164.06 APE8-dihe-out -111.55, -13.91 APE8-rot-out 80.18 APE67-dihe-out -157.27, 123.12 -113.49, 175.2 APE12-dist-out 17.7535 APE11-dist-out 19.5873 APE10-dist-out 21.2162 APE9-dist-out 13.438 S218A,S222A None None XRAY 3.16 0.188 0.234 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0v STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0VA P15056 449 722 766.0 ANP:801 ATPlike Inactive DFGin 5.7413 13.2905 BLBplus -118.84, -178.01 61.17, 44.22 -99.98, 160.93 40.29, 99.45 62.33, -140.62 out-out out 14.1107 Saltbr-out 13.1408 HRD-in -76.68, -47.66 79.51, -34.29 out-out-out SNCooo out-out ActLoopNT-out 9.3238 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooo APE10-dihe-na -140.71, 145.59 APE9-dihe-na 81.77, -131.39 APE8-dihe-in -106.29, 148.31 APE8-rot-out 201.4 APE67-dihe-in -54.29, -30.39 -107.29, -13.89 APE12-dist-in 13.9087 APE11-dist-out 15.7766 APE10-dist-out 12.613 APE9-dist-out 10.1626 None None None XRAY 3.16 0.188 0.234 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0v TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0V — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0VB Q02750 42 383 393.0 ANP:801,EUI:803 ATPlike,Type3 Inactive DFGin 6.0381 13.7379 BLBplus -152.98, 176.74 51.89, 40.05 -97.58, 155.01 48.54, 94.68 -74.32, 76.65 out-out out 15.3562 Saltbr-out 15.2475 HRD-in -53.62, -41.23 79.48, -8.01 out-out-out SNCooo out-out ActLoopNT-out 8.4508 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -59.78, 136.18 APE9-dihe-na -90.07, -164.06 APE8-dihe-out -111.55, -13.91 APE8-rot-out 80.18 APE67-dihe-out -157.27, 123.12 -113.49, 175.2 APE12-dist-out 17.7535 APE11-dist-out 19.5873 APE10-dist-out 21.2162 APE9-dist-out 13.438 S218A,S222A None None XRAY 3.16 0.188 0.234 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0v Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0VA P15056 449 722 766.0 ANP:801 ATPlike Inactive DFGin 5.7413 13.2905 BLBplus -118.84, -178.01 61.17, 44.22 -99.98, 160.93 40.29, 99.45 62.33, -140.62 out-out out 14.1107 Saltbr-out 13.1408 HRD-in -76.68, -47.66 79.51, -34.29 out-out-out SNCooo out-out ActLoopNT-out 9.3238 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooo APE10-dihe-na -140.71, 145.59 APE9-dihe-na 81.77, -131.39 APE8-dihe-in -106.29, 148.31 APE8-rot-out 201.4 APE67-dihe-in -54.29, -30.39 -107.29, -13.89 APE12-dist-in 13.9087 APE11-dist-out 15.7766 APE10-dist-out 12.613 APE9-dist-out 10.1626 None None None XRAY 3.16 0.188 0.234 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0v Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0V — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name