PDB: 7M0U — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0UB Q02750 43 385 393.0 QO7:501,ANP:502 Type3,ATPlike Inactive DFGin 6.1782 13.8403 BLBplus -152.87, -177.82 54.02, 43.66 -96.33, 148.45 42.9, 86.91 -71.94, 82.66 out-out out 15.4928 Saltbr-out 15.6637 HRD-in -60.41, -57.85 71.46, -3.21 out-out-out SNCooo out-out ActLoopNT-out 9.0481 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -60.78, 138.09 APE9-dihe-na -86.76, -175.69 APE8-dihe-out -100.26, -15.57 APE8-rot-out 49.06 APE67-dihe-out -118.78, 147.11 -163.65, 150.46 APE12-dist-out 17.2011 APE11-dist-out 22.3588 APE10-dist-out 23.5662 APE9-dist-out 13.6379 S218A,S222A None None XRAY 3.09 0.193 0.23 B 397.0 311.0 32 26 26 0 [[68, 361]] 1.0 7m0u STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0UA P15056 449 722 766.0 ANP:801 ATPlike Inactive DFGin 5.8262 13.5453 BLBplus -114.76, -174.76 53.19, 33.71 -86.73, 158.23 49.19, 93.22 61.58, -136.88 out-out out 14.5076 Saltbr-out 13.6281 HRD-in -66.62, -51.93 79.28, -5.3 out-out-out SNCooo out-out ActLoopNT-out 8.9683 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -137.94, 171.17 APE9-dihe-na 125.59, 173.92 APE8-dihe-in -78.53, 136.46 APE8-rot-out 49.62 APE67-dihe-in -63.36, -26.84 -75.55, -22.51 APE12-dist-out 14.5901 APE11-dist-out 14.4763 APE10-dist-out 12.1021 APE9-dist-out 6.3314 None None None XRAY 3.09 0.193 0.23 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0u TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0U — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0UB Q02750 43 385 393.0 QO7:501,ANP:502 Type3,ATPlike Inactive DFGin 6.1782 13.8403 BLBplus -152.87, -177.82 54.02, 43.66 -96.33, 148.45 42.9, 86.91 -71.94, 82.66 out-out out 15.4928 Saltbr-out 15.6637 HRD-in -60.41, -57.85 71.46, -3.21 out-out-out SNCooo out-out ActLoopNT-out 9.0481 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -60.78, 138.09 APE9-dihe-na -86.76, -175.69 APE8-dihe-out -100.26, -15.57 APE8-rot-out 49.06 APE67-dihe-out -118.78, 147.11 -163.65, 150.46 APE12-dist-out 17.2011 APE11-dist-out 22.3588 APE10-dist-out 23.5662 APE9-dist-out 13.6379 S218A,S222A None None XRAY 3.09 0.193 0.23 B 397.0 311.0 32 26 26 0 [[68, 361]] 1.0 7m0u Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0UA P15056 449 722 766.0 ANP:801 ATPlike Inactive DFGin 5.8262 13.5453 BLBplus -114.76, -174.76 53.19, 33.71 -86.73, 158.23 49.19, 93.22 61.58, -136.88 out-out out 14.5076 Saltbr-out 13.6281 HRD-in -66.62, -51.93 79.28, -5.3 out-out-out SNCooo out-out ActLoopNT-out 8.9683 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -137.94, 171.17 APE9-dihe-na 125.59, 173.92 APE8-dihe-in -78.53, 136.46 APE8-rot-out 49.62 APE67-dihe-in -63.36, -26.84 -75.55, -22.51 APE12-dist-out 14.5901 APE11-dist-out 14.4763 APE10-dist-out 12.1021 APE9-dist-out 6.3314 None None None XRAY 3.09 0.193 0.23 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0u Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0U — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name