PDB: 7M0T — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0TA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0TB Q02750 42 383 393.0 3EW:401,ANP:402 Type3,ATPlike Inactive DFGin 6.0753 13.7095 BLBplus -159.9, -178.5 64.02, 41.63 -104.3, 143.17 46.34, 100.82 -64.54, 70.24 out-out out 15.4777 Saltbr-out 16.3323 HRD-in -53.73, -55.69 69.68, 5.22 out-out-out SNCooo out-out ActLoopNT-out 8.8715 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -40.91, 141.26 APE9-dihe-na -101.18, -177.28 APE8-dihe-out -68.44, -50.32 APE8-rot-in 321.79 APE67-dihe-out -148.38, 132.66 -145.97, 175.15 APE12-dist-out 17.1657 APE11-dist-out 22.6476 APE10-dist-out 23.7095 APE9-dist-out 13.8641 S218A,S222A None None XRAY 3.19 0.199 0.254 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0t STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0TA P15056 448 721 766.0 ANP:801 ATPlike Inactive DFGin 5.4827 13.6452 BLBplus -101.53, -171.54 49.12, 40.35 -93.39, 158.36 49.68, 91.24 67.74, -141.33 out-out out 14.6334 Saltbr-out 13.4177 HRD-in -63.36, -50.98 81.19, -14.99 out-out-out SNCooo out-out ActLoopNT-out 9.0962 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_iooo APE10-dihe-na -146.63, 169.35 APE9-dihe-na 113.78, -178.56 APE8-dihe-in -87.12, 141.18 APE8-rot-out 208.64 APE67-dihe-out -59.38, 160.81 -70.93, -34.96 APE12-dist-in 13.663 APE11-dist-out 15.2769 APE10-dist-out 12.4492 APE9-dist-out 6.6885 None None None XRAY 3.19 0.199 0.254 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0t TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0T — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 7M0TA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 7M0TB Q02750 42 383 393.0 3EW:401,ANP:402 Type3,ATPlike Inactive DFGin 6.0753 13.7095 BLBplus -159.9, -178.5 64.02, 41.63 -104.3, 143.17 46.34, 100.82 -64.54, 70.24 out-out out 15.4777 Saltbr-out 16.3323 HRD-in -53.73, -55.69 69.68, 5.22 out-out-out SNCooo out-out ActLoopNT-out 8.8715 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -40.91, 141.26 APE9-dihe-na -101.18, -177.28 APE8-dihe-out -68.44, -50.32 APE8-rot-in 321.79 APE67-dihe-out -148.38, 132.66 -145.97, 175.15 APE12-dist-out 17.1657 APE11-dist-out 22.6476 APE10-dist-out 23.7095 APE9-dist-out 13.8641 S218A,S222A None None XRAY 3.19 0.199 0.254 B 397.0 310.0 32 26 26 0 [[68, 361]] 1.0 7m0t Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 7M0TA P15056 448 721 766.0 ANP:801 ATPlike Inactive DFGin 5.4827 13.6452 BLBplus -101.53, -171.54 49.12, 40.35 -93.39, 158.36 49.68, 91.24 67.74, -141.33 out-out out 14.6334 Saltbr-out 13.4177 HRD-in -63.36, -50.98 81.19, -14.99 out-out-out SNCooo out-out ActLoopNT-out 9.0962 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_iooo APE10-dihe-na -146.63, 169.35 APE9-dihe-na 113.78, -178.56 APE8-dihe-in -87.12, 141.18 APE8-rot-out 208.64 APE67-dihe-out -59.38, 160.81 -70.93, -34.96 APE12-dist-in 13.663 APE11-dist-out 15.2769 APE10-dist-out 12.4492 APE9-dist-out 6.6885 None None None XRAY 3.19 0.199 0.254 A 283.0 274.0 0 30 30 0 [[457, 716]] 1.0 7m0t Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 7M0T — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name