PDB: 6V2W — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6V2WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6V2WB Q02750 40 383 393.0 ANP:801 ATPlike Inactive DFGin 5.8394 13.8006 BLBplus -157.59, 169.08 49.06, 44.93 -84.24, 160.32 41.65, 89.8 -73.89, 81.99 out-out out 15.4976 Saltbr-out 15.9009 HRD-in -69.45, -57.02 68.3, 7.65 out-out-out SNCooo out-out ActLoopNT-out 8.701 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -54.4, 144.31 APE9-dihe-na -89.17, -161.86 APE8-dihe-out -115.14, -20.62 APE8-rot-out 48.82 APE67-dihe-out -139.36, 135.26 -146.31, 162.2 APE12-dist-out 17.533 APE11-dist-out 22.7363 APE10-dist-out 24.0164 APE9-dist-out 13.6453 S218A,S222A None None XRAY 3.12 0.189 0.237 B 397.0 312.0 32 26 26 0 [[68, 361]] 1.0 6v2w STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6V2WA P15056 447 721 766.0 ANP:801 ATPlike Inactive DFGin 5.532 13.7036 BLBplus -135.72, 175.83 57.63, 35.46 -91.96, 158.82 53.8, 96.09 64.15, -137.39 out-out out 14.4746 Saltbr-out 12.4333 HRD-in -69.37, -44.53 66.04, 8.13 out-out-out SNCooo out-out ActLoopNT-out 8.9897 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -146.39, 170.31 APE9-dihe-na 111.41, -172.95 APE8-dihe-in -92.84, 135.37 APE8-rot-out 52.69 APE67-dihe-in -65.1, -26.74 -72.43, -22.76 APE12-dist-out 14.7285 APE11-dist-out 14.8979 APE10-dist-out 12.1593 APE9-dist-out 6.2561 None None None XRAY 3.12 0.189 0.237 A 283.0 275.0 0 30 30 0 [[457, 716]] 1.0 6v2w TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6V2W — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6V2WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6V2WB Q02750 40 383 393.0 ANP:801 ATPlike Inactive DFGin 5.8394 13.8006 BLBplus -157.59, 169.08 49.06, 44.93 -84.24, 160.32 41.65, 89.8 -73.89, 81.99 out-out out 15.4976 Saltbr-out 15.9009 HRD-in -69.45, -57.02 68.3, 7.65 out-out-out SNCooo out-out ActLoopNT-out 8.701 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -54.4, 144.31 APE9-dihe-na -89.17, -161.86 APE8-dihe-out -115.14, -20.62 APE8-rot-out 48.82 APE67-dihe-out -139.36, 135.26 -146.31, 162.2 APE12-dist-out 17.533 APE11-dist-out 22.7363 APE10-dist-out 24.0164 APE9-dist-out 13.6453 S218A,S222A None None XRAY 3.12 0.189 0.237 B 397.0 312.0 32 26 26 0 [[68, 361]] 1.0 6v2w Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6V2WA P15056 447 721 766.0 ANP:801 ATPlike Inactive DFGin 5.532 13.7036 BLBplus -135.72, 175.83 57.63, 35.46 -91.96, 158.82 53.8, 96.09 64.15, -137.39 out-out out 14.4746 Saltbr-out 12.4333 HRD-in -69.37, -44.53 66.04, 8.13 out-out-out SNCooo out-out ActLoopNT-out 8.9897 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -146.39, 170.31 APE9-dihe-na 111.41, -172.95 APE8-dihe-in -92.84, 135.37 APE8-rot-out 52.69 APE67-dihe-in -65.1, -26.74 -72.43, -22.76 APE12-dist-out 14.7285 APE11-dist-out 14.8979 APE10-dist-out 12.1593 APE9-dist-out 6.2561 None None None XRAY 3.12 0.189 0.237 A 283.0 275.0 0 30 30 0 [[457, 716]] 1.0 6v2w Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6V2W — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name