PDB: 6U2G — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6U2GB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6U2GA Q02750 43 383 393.0 ACP:901 ATPlike Inactive DFGin 5.8079 13.8406 BLBplus -143.7, 174.8 53.7, 47.78 -98.62, 156.52 46.78, 97.62 -76.59, 70.13 out-out out 15.3736 Saltbr-out 14.8686 HRD-in -83.28, -55.76 76.37, -10.26 out-out-out SNCooo out-out ActLoopNT-out 9.207 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -64.24, 146.48 APE9-dihe-na -101.23, -173.03 APE8-dihe-out -114.34, -9.62 APE8-rot-out 55.71 APE67-dihe-out -148.86, 141.69 -149.81, 176.75 APE12-dist-out 19.1865 APE11-dist-out 17.9815 APE10-dist-out 22.1053 APE9-dist-out 12.9996 None None None XRAY 2.886 0.231 0.276 A 394.0 309.0 32 26 26 0 [[68, 361]] 1.0 6u2g STE_MAP2K1_HUMAN STE 2.4e-97 331.4 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6U2GB P15056 451 722 766.0 ACP:901 ATPlike Inactive DFGin 6.1502 13.9094 BLBplus -127.14, -173.09 46.65, 53.2 -113.93, 152.92 52.73, 94.7 72.25, -152.99 out-out out 14.6056 Saltbr-out 12.7046 HRD-in -59.19, -53.53 76.48, -9.73 out-out-out SNCooo out-out ActLoopNT-out 9.495 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -146.07, 161.59 APE9-dihe-na 90.18, -141.72 APE8-dihe-in -101.38, 139.04 APE8-rot-out 180.97 APE67-dihe-in -60.58, -31.67 -70.85, -22.56 APE12-dist-out 15.3356 APE11-dist-out 15.7094 APE10-dist-out 13.5919 APE9-dist-out 9.8922 None None None XRAY 2.886 0.231 0.276 B 307.0 264.0 8 30 22 8 [[457, 716]] 1.0 6u2g TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6U2G — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6U2GB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6U2GA Q02750 43 383 393.0 ACP:901 ATPlike Inactive DFGin 5.8079 13.8406 BLBplus -143.7, 174.8 53.7, 47.78 -98.62, 156.52 46.78, 97.62 -76.59, 70.13 out-out out 15.3736 Saltbr-out 14.8686 HRD-in -83.28, -55.76 76.37, -10.26 out-out-out SNCooo out-out ActLoopNT-out 9.207 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -64.24, 146.48 APE9-dihe-na -101.23, -173.03 APE8-dihe-out -114.34, -9.62 APE8-rot-out 55.71 APE67-dihe-out -148.86, 141.69 -149.81, 176.75 APE12-dist-out 19.1865 APE11-dist-out 17.9815 APE10-dist-out 22.1053 APE9-dist-out 12.9996 None None None XRAY 2.886 0.231 0.276 A 394.0 309.0 32 26 26 0 [[68, 361]] 1.0 6u2g Homo sapiens STE_MAP2K1_HUMAN STE 2.4e-97 331.4 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6U2GB P15056 451 722 766.0 ACP:901 ATPlike Inactive DFGin 6.1502 13.9094 BLBplus -127.14, -173.09 46.65, 53.2 -113.93, 152.92 52.73, 94.7 72.25, -152.99 out-out out 14.6056 Saltbr-out 12.7046 HRD-in -59.19, -53.53 76.48, -9.73 out-out-out SNCooo out-out ActLoopNT-out 9.495 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -146.07, 161.59 APE9-dihe-na 90.18, -141.72 APE8-dihe-in -101.38, 139.04 APE8-rot-out 180.97 APE67-dihe-in -60.58, -31.67 -70.85, -22.56 APE12-dist-out 15.3356 APE11-dist-out 15.7094 APE10-dist-out 13.5919 APE9-dist-out 9.8922 None None None XRAY 2.886 0.231 0.276 B 307.0 264.0 8 30 22 8 [[457, 716]] 1.0 6u2g Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6U2G — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name