KinCore

PDB: 6R5F — TKL RIPK1_HUMAN

Total number of chains: 4

Active chains: 0

Total number of genes: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGout	BBAminus	4	100.0%	6R5FB

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
TKL	RIPK1	RIPK1_HUMAN	6R5FA	Q13546	9	294	671.0	JSW:301	Type3	Inactive	DFGout	13.955	9.481	BBAminus	-112.95, 165.41	-130.42, 63.72	-66.93, -21.93	297.24, 0.02	-91.89, 5.73	out-out	out	14.529	Saltbr-out	13.191	HRD-in	-56.51, -60.39	80.9, -22.8	out-out-out	SNCooo	out-out	ActLoopNT-out	5.924	ActLoopCT-out	nonTYR	APEdihe_aanoi	APEdist_nnnn	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, 999.0	APE8-dihe-none	999.0, 136.38	APE8-rot-out	178.71	APE67-dihe-in	-64.62, -25.33	-74.5, -6.75	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-none	999.0	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	A	303	252	34	0	0	16	[[17, 287]]	1.0	6r5f	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1
TKL	RIPK1	RIPK1_HUMAN	6R5FB	Q13546	10	294	671.0	JSW:301	Type3	Inactive	DFGout	13.78	9.691	BBAminus	-117.91, 170.03	-135.39, 68.26	-70.88, -17.07	303.86, 8.01	-86.89, -7.53	out-out	out	14.147	Saltbr-out	14.183	HRD-in	-58.11, -56.03	90.31, -47.38	out-out-out	SNCooo	out-out	ActLoopNT-out	6.22	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_nnno	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, 132.8	APE8-dihe-in	-110.24, 128.64	APE8-rot-out	54.88	APE67-dihe-in	-53.24, -34.36	-61.38, -32.96	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-out	8.919	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	B	303	256	29	0	0	17	[[17, 287]]	1.0	6r5f	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1
TKL	RIPK1	RIPK1_HUMAN	6R5FC	Q13546	9	294	671.0	JSW:301	Type3	Inactive	DFGout	13.993	9.934	BBAminus	-129.98, 154.77	-113.58, 87.15	-77.89, -25.03	313.32, 1.4	-85.25, 0.11	out-out	out	14.529	Saltbr-out	15.039	HRD-in	-68.31, -36.48	72.06, -57.73	out-out-out	SNCooo	out-out	ActLoopNT-out	5.739	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_nnno	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, -139.85	APE8-dihe-in	-109.8, 132.44	APE8-rot-out	61.03	APE67-dihe-in	-41.51, -34.43	-97.85, -8.61	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-out	11.153	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	C	303	253	33	0	0	16	[[17, 287]]	1.0	6r5f	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1
TKL	RIPK1	RIPK1_HUMAN	6R5FD	Q13546	11	294	671.0	JSW:301	Type3	Inactive	DFGout	14.45	9.248	BBAminus	-142.39, 170.94	-125.26, 78.91	-70.36, -35.3	283.29, 144.33	-66.46, -23.13	out-out	out	15.019	Saltbr-out	16.123	HRD-in	-59.61, -37.57	70.15, -52.85	out-out-out	SNCooo	out-out	ActLoopNT-out	6.06	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_nnno	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, 119.22	APE8-dihe-in	-103.39, 137.53	APE8-rot-out	189.96	APE67-dihe-in	-50.68, -36.72	-90.03, -10.98	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-out	10.433	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	D	303	250	34	0	0	17	[[17, 287]]	1.0	6r5f	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1

PDB: 6R5F — TKL RIPK1_HUMAN

Total number of chains: 4

Active chains: 0

Total number of genes: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGout	BBAminus	4	100.0%	6R5FB

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
TKL	RIPK1	RIPK1_HUMAN	6R5FA	Q13546	9	294	671.0	JSW:301	Type3	Inactive	DFGout	13.955	9.481	BBAminus	-112.95, 165.41	-130.42, 63.72	-66.93, -21.93	297.24, 0.02	-91.89, 5.73	out-out	out	14.529	Saltbr-out	13.191	HRD-in	-56.51, -60.39	80.9, -22.8	out-out-out	SNCooo	out-out	ActLoopNT-out	5.924	ActLoopCT-out	nonTYR	APEdihe_aanoi	APEdist_nnnn	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, 999.0	APE8-dihe-none	999.0, 136.38	APE8-rot-out	178.71	APE67-dihe-in	-64.62, -25.33	-74.5, -6.75	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-none	999.0	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	A	303	252	34	0	0	16	[[17, 287]]	1.0	6r5f	Homo sapiens	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1
TKL	RIPK1	RIPK1_HUMAN	6R5FB	Q13546	10	294	671.0	JSW:301	Type3	Inactive	DFGout	13.78	9.691	BBAminus	-117.91, 170.03	-135.39, 68.26	-70.88, -17.07	303.86, 8.01	-86.89, -7.53	out-out	out	14.147	Saltbr-out	14.183	HRD-in	-58.11, -56.03	90.31, -47.38	out-out-out	SNCooo	out-out	ActLoopNT-out	6.22	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_nnno	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, 132.8	APE8-dihe-in	-110.24, 128.64	APE8-rot-out	54.88	APE67-dihe-in	-53.24, -34.36	-61.38, -32.96	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-out	8.919	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	B	303	256	29	0	0	17	[[17, 287]]	1.0	6r5f	Homo sapiens	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1
TKL	RIPK1	RIPK1_HUMAN	6R5FC	Q13546	9	294	671.0	JSW:301	Type3	Inactive	DFGout	13.993	9.934	BBAminus	-129.98, 154.77	-113.58, 87.15	-77.89, -25.03	313.32, 1.4	-85.25, 0.11	out-out	out	14.529	Saltbr-out	15.039	HRD-in	-68.31, -36.48	72.06, -57.73	out-out-out	SNCooo	out-out	ActLoopNT-out	5.739	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_nnno	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, -139.85	APE8-dihe-in	-109.8, 132.44	APE8-rot-out	61.03	APE67-dihe-in	-41.51, -34.43	-97.85, -8.61	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-out	11.153	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	C	303	253	33	0	0	16	[[17, 287]]	1.0	6r5f	Homo sapiens	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1
TKL	RIPK1	RIPK1_HUMAN	6R5FD	Q13546	11	294	671.0	JSW:301	Type3	Inactive	DFGout	14.45	9.248	BBAminus	-142.39, 170.94	-125.26, 78.91	-70.36, -35.3	283.29, 144.33	-66.46, -23.13	out-out	out	15.019	Saltbr-out	16.123	HRD-in	-59.61, -37.57	70.15, -52.85	out-out-out	SNCooo	out-out	ActLoopNT-out	6.06	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_nnno	APE10-dihe-na	999.0, 999.0	APE9-dihe-na	999.0, 119.22	APE8-dihe-in	-103.39, 137.53	APE8-rot-out	189.96	APE67-dihe-in	-50.68, -36.72	-90.03, -10.98	APE12-dist-none	999.0	APE11-dist-none	999.0	APE10-dist-none	999.0	APE9-dist-out	10.433	C34A,C127A,C233A,C240A	None	None	XRAY	3.25	0.245	0.289	D	303	250	34	0	0	17	[[17, 287]]	1.0	6r5f	Homo sapiens	TKL_RIPK1_HUMAN	TKL	1.4e-72	250.4	6	265	260	155	156	157	159	161	45	63	67	135	137	136	138	210	196	191	190	189	188	187	186	185	93	Receptor-interacting serine/threonine-protein kinase 1

PDB: 6R5F — TKL RIPK1_HUMAN

Total number of chains: 0

Active chains: 0

Total number of genes: 0

Spatial label	Dihedral label	Number of Chains	Percent	Representative

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name