PDB: 6PP9 — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6PP9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6PP9B Q02750 38 383 393.0 ANP:801,LCJ:803 ATPlike,Type3 Inactive DFGin 6.0507 13.8503 BLBplus -152.52, 171.62 57.53, 41.01 -92.48, 164.33 45.1, 87.01 -81.4, 67.83 out-out out 15.4693 Saltbr-out 15.3255 HRD-in -69.19, -57.7 73.02, -1.06 out-out-out SNCooo out-out ActLoopNT-out 8.325 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -150.75, 155.46 APE9-dihe-na -104.35, -179.3 APE8-dihe-out -103.86, -21.71 APE8-rot-out 60.0 APE67-dihe-out -161.36, 138.21 -120.01, -175.99 APE12-dist-out 17.6293 APE11-dist-out 18.0984 APE10-dist-out 21.1907 APE9-dist-out 12.1845 S218A,S222A None None XRAY 2.59 0.222 0.245 B 397.0 314.0 32 26 26 0 [[68, 361]] 1.0 6pp9 STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6PP9A P15056 447 722 766.0 ANP:801 ATPlike Inactive DFGin 5.3423 13.4984 BLBplus -130.79, 177.54 57.37, 43.96 -96.57, 156.54 49.86, 89.0 63.47, -135.71 out-out out 14.313 Saltbr-out 12.6898 HRD-in -66.97, -47.8 65.51, 3.6 out-out-out SNCooo out-out ActLoopNT-out 9.2557 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -142.44, 146.23 APE9-dihe-na 73.26, -154.57 APE8-dihe-in -71.36, 154.2 APE8-rot-out 182.15 APE67-dihe-in -61.64, -19.53 -112.25, -5.75 APE12-dist-out 15.2013 APE11-dist-out 15.9004 APE10-dist-out 12.6934 APE9-dist-out 10.139 None None None XRAY 2.59 0.222 0.245 A 283.0 276.0 0 30 30 0 [[457, 716]] 1.0 6pp9 TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6PP9 — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6PP9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6PP9B Q02750 38 383 393.0 ANP:801,LCJ:803 ATPlike,Type3 Inactive DFGin 6.0507 13.8503 BLBplus -152.52, 171.62 57.53, 41.01 -92.48, 164.33 45.1, 87.01 -81.4, 67.83 out-out out 15.4693 Saltbr-out 15.3255 HRD-in -69.19, -57.7 73.02, -1.06 out-out-out SNCooo out-out ActLoopNT-out 8.325 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -150.75, 155.46 APE9-dihe-na -104.35, -179.3 APE8-dihe-out -103.86, -21.71 APE8-rot-out 60.0 APE67-dihe-out -161.36, 138.21 -120.01, -175.99 APE12-dist-out 17.6293 APE11-dist-out 18.0984 APE10-dist-out 21.1907 APE9-dist-out 12.1845 S218A,S222A None None XRAY 2.59 0.222 0.245 B 397.0 314.0 32 26 26 0 [[68, 361]] 1.0 6pp9 Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.2 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6PP9A P15056 447 722 766.0 ANP:801 ATPlike Inactive DFGin 5.3423 13.4984 BLBplus -130.79, 177.54 57.37, 43.96 -96.57, 156.54 49.86, 89.0 63.47, -135.71 out-out out 14.313 Saltbr-out 12.6898 HRD-in -66.97, -47.8 65.51, 3.6 out-out-out SNCooo out-out ActLoopNT-out 9.2557 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -142.44, 146.23 APE9-dihe-na 73.26, -154.57 APE8-dihe-in -71.36, 154.2 APE8-rot-out 182.15 APE67-dihe-in -61.64, -19.53 -112.25, -5.75 APE12-dist-out 15.2013 APE11-dist-out 15.9004 APE10-dist-out 12.6934 APE9-dist-out 10.139 None None None XRAY 2.59 0.222 0.245 A 283.0 276.0 0 30 30 0 [[457, 716]] 1.0 6pp9 Homo sapiens TKL_BRAF_HUMAN TKL 8.1e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6PP9 — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name