PDB: 6NYB — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6NYBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6NYBB Q02750 56 383 393.0 ADP:60601,LCJ:60901 ATPlike,Type3 Inactive DFGin 5.9588 14.0365 BLBplus -152.28, 170.52 57.47, 42.76 -92.93, 161.49 47.46, 85.53 -88.41, 68.49 out-out out 15.4696 Saltbr-out 17.6022 HRD-in -56.15, -54.04 65.39, 11.35 out-out-out SNCooo out-out ActLoopNT-out 8.2916 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -140.81, 127.27 APE9-dihe-na -93.66, 157.79 APE8-dihe-out -110.82, -26.16 APE8-rot-out 55.56 APE67-dihe-out -130.29, 148.43 -119.13, 133.87 APE12-dist-out 17.78 APE11-dist-out 18.3191 APE10-dist-out 22.3789 APE9-dist-out 12.1589 S218A,S222A None None EM 4.1 999.0 999.0 B 415.0 289.0 39 26 26 0 [[68, 361]] 1.0 6nyb STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6NYBA P15056 233 738 766.0 AGS:60801 ATPlike Inactive DFGin 5.4979 13.825 BLBplus -130.99, 171.98 57.42, 47.58 -103.38, 154.64 56.0, 92.93 63.13, -128.72 out-out out 13.8238 Saltbr-out 12.6037 HRD-in -73.31, -44.18 67.31, 1.32 out-out-out SNCooo out-out ActLoopNT-out 9.0654 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -162.22, 166.73 APE9-dihe-na 98.18, -110.24 APE8-dihe-in -136.25, 146.51 APE8-rot-out 61.57 APE67-dihe-in -62.67, -27.04 -119.01, -4.59 APE12-dist-out 14.6597 APE11-dist-out 15.6406 APE10-dist-out 13.8824 APE9-dist-out 8.7627 None SEP365,SEP729 SEP365,SEP729 EM 4.1 999.0 999.0 A 805.0 350.0 0 30 30 0 [[457, 716]] 1.0 6nyb TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6NYB — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6NYBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6NYBB Q02750 56 383 393.0 ADP:60601,LCJ:60901 ATPlike,Type3 Inactive DFGin 5.9588 14.0365 BLBplus -152.28, 170.52 57.47, 42.76 -92.93, 161.49 47.46, 85.53 -88.41, 68.49 out-out out 15.4696 Saltbr-out 17.6022 HRD-in -56.15, -54.04 65.39, 11.35 out-out-out SNCooo out-out ActLoopNT-out 8.2916 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -140.81, 127.27 APE9-dihe-na -93.66, 157.79 APE8-dihe-out -110.82, -26.16 APE8-rot-out 55.56 APE67-dihe-out -130.29, 148.43 -119.13, 133.87 APE12-dist-out 17.78 APE11-dist-out 18.3191 APE10-dist-out 22.3789 APE9-dist-out 12.1589 S218A,S222A None None EM 4.1 999.0 999.0 B 415.0 289.0 39 26 26 0 [[68, 361]] 1.0 6nyb Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6NYBA P15056 233 738 766.0 AGS:60801 ATPlike Inactive DFGin 5.4979 13.825 BLBplus -130.99, 171.98 57.42, 47.58 -103.38, 154.64 56.0, 92.93 63.13, -128.72 out-out out 13.8238 Saltbr-out 12.6037 HRD-in -73.31, -44.18 67.31, 1.32 out-out-out SNCooo out-out ActLoopNT-out 9.0654 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -162.22, 166.73 APE9-dihe-na 98.18, -110.24 APE8-dihe-in -136.25, 146.51 APE8-rot-out 61.57 APE67-dihe-in -62.67, -27.04 -119.01, -4.59 APE12-dist-out 14.6597 APE11-dist-out 15.6406 APE10-dist-out 13.8824 APE9-dist-out 8.7627 None SEP365,SEP729 SEP365,SEP729 EM 4.1 999.0 999.0 A 805.0 350.0 0 30 30 0 [[457, 716]] 1.0 6nyb Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6NYB — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name