PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 5X2AB
DFGin BLBplus 1 25.0% 5X2AD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5X2AD P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 4.567 13.491 BLBplus -132.47, 164.02 73.22, 18.47 -66.23, 142.03 48.39, 91.71 77.4, 1.26 out-out out 13.992 Saltbr-out 14.35 HRD-in -72.94, -56.49 82.37, -10.91 out-out-out SNCooo out-out ActLoopNT-out 6.463 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 3.06 APE9-dihe-in -69.62, 129.82 APE8-dihe-in -83.4, 65.28 APE8-rot-na 22.72 APE67-dihe-in -72.49, -3.02 -53.67, -40.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.897 APE9-dist-out 8.235 T790M,V948R None None XRAY 1.85 0.176 0.219 D 331 297 13 0 0 10 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC P00533 700 1015 1210.0 7XO:1104 Type1 Inactive DFGin 5.504 16.539 BLBtrans -121.56, -177.75 69.47, 12.59 -60.5, 141.21 167.5, 68.5 89.76, -35.23 out-out out 13.565 Saltbr-out 13.137 HRD-in -66.9, -48.76 80.92, -13.83 out-out-out SNCooo out-out ActLoopNT-out 7.021 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.32 APE8-dihe-in -80.48, 64.62 APE8-rot-na 38.22 APE67-dihe-in -72.09, -6.11 -53.33, -40.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.214 T790M,V948R None None XRAY 1.85 0.176 0.219 C 331 303 13 0 0 13 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB P00533 700 1022 1210.0 7XO:1105,ANP:1106 Type1,ATPlike Inactive DFGin 5.521 16.379 BLBtrans -118.08, 178.13 68.28, 22.21 -63.57, 132.1 161.37, 67.84 99.95, -15.3 out-out out 13.892 Saltbr-out 13.505 HRD-in -67.87, -49.57 81.65, -13.01 out-out-out SNCooo out-out ActLoopNT-out 6.364 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -63.35, -22.61 APE9-dihe-in -95.03, 108.56 APE8-dihe-in -83.98, 72.85 APE8-rot-na 21.28 APE67-dihe-in -71.39, -9.89 -59.75, -39.3 APE12-dist-na 15.726 APE11-dist-na 13.245 APE10-dist-na 9.274 APE9-dist-in 7.568 T790M,V948R None None XRAY 1.85 0.176 0.219 B 331 322 0 0 0 0 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA P00533 700 1011 1210.0 7XO:1107,ANP:1108 Type1,Allosteric Inactive DFGin 5.565 16.303 BLBtrans -120.52, 179.71 70.51, 14.21 -61.87, 136.6 165.52, 70.66 90.66, -18.93 out-out out 13.778 Saltbr-out 13.104 HRD-in -79.48, -46.8 73.07, -8.08 out-out-none SNCoon out-none ActLoopNT-out 6.728 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 152.51 APE8-dihe-in -84.48, 76.35 APE8-rot-na 26.1 APE67-dihe-in -71.21, -12.48 -60.14, -38.61 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.762 T790M,V948R None None XRAY 1.85 0.176 0.219 A 331 297 13 0 0 13 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 5X2AB
DFGin BLBplus 1 25.0% 5X2AD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5X2AD P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 4.567 13.491 BLBplus -132.47, 164.02 73.22, 18.47 -66.23, 142.03 48.39, 91.71 77.4, 1.26 out-out out 13.992 Saltbr-out 14.35 HRD-in -72.94, -56.49 82.37, -10.91 out-out-out SNCooo out-out ActLoopNT-out 6.463 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 3.06 APE9-dihe-in -69.62, 129.82 APE8-dihe-in -83.4, 65.28 APE8-rot-na 22.72 APE67-dihe-in -72.49, -3.02 -53.67, -40.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.897 APE9-dist-out 8.235 T790M,V948R None None XRAY 1.85 0.176 0.219 D 331 297 13 0 0 10 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC P00533 700 1015 1210.0 7XO:1104 Type1 Inactive DFGin 5.504 16.539 BLBtrans -121.56, -177.75 69.47, 12.59 -60.5, 141.21 167.5, 68.5 89.76, -35.23 out-out out 13.565 Saltbr-out 13.137 HRD-in -66.9, -48.76 80.92, -13.83 out-out-out SNCooo out-out ActLoopNT-out 7.021 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.32 APE8-dihe-in -80.48, 64.62 APE8-rot-na 38.22 APE67-dihe-in -72.09, -6.11 -53.33, -40.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.214 T790M,V948R None None XRAY 1.85 0.176 0.219 C 331 303 13 0 0 13 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB P00533 700 1022 1210.0 7XO:1105,ANP:1106 Type1,ATPlike Inactive DFGin 5.521 16.379 BLBtrans -118.08, 178.13 68.28, 22.21 -63.57, 132.1 161.37, 67.84 99.95, -15.3 out-out out 13.892 Saltbr-out 13.505 HRD-in -67.87, -49.57 81.65, -13.01 out-out-out SNCooo out-out ActLoopNT-out 6.364 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -63.35, -22.61 APE9-dihe-in -95.03, 108.56 APE8-dihe-in -83.98, 72.85 APE8-rot-na 21.28 APE67-dihe-in -71.39, -9.89 -59.75, -39.3 APE12-dist-na 15.726 APE11-dist-na 13.245 APE10-dist-na 9.274 APE9-dist-in 7.568 T790M,V948R None None XRAY 1.85 0.176 0.219 B 331 322 0 0 0 0 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA P00533 700 1011 1210.0 7XO:1107,ANP:1108 Type1,Allosteric Inactive DFGin 5.565 16.303 BLBtrans -120.52, 179.71 70.51, 14.21 -61.87, 136.6 165.52, 70.66 90.66, -18.93 out-out out 13.778 Saltbr-out 13.104 HRD-in -79.48, -46.8 73.07, -8.08 out-out-none SNCoon out-none ActLoopNT-out 6.728 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 152.51 APE8-dihe-in -84.48, 76.35 APE8-rot-na 26.1 APE67-dihe-in -71.21, -12.48 -60.14, -38.61 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.762 T790M,V948R None None XRAY 1.85 0.176 0.219 A 331 297 13 0 0 13 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name